Work is a special environment that only permits sterilized conversation in order to keep everyone in harmony. Therefore, navigating politics is important. If the issue revolves around ethics, fiduciary responsibility, or accountability and responsibility, stand up for your convictions. If the issue is a political hot potato that does not involve or affect you or cause anyone any egregious harm, shut your piehole. If you have a measure of authority, influence, a good reputation, and a good internal following, by all means speak on behalf of the right causes.
In short, as the wise gentleman above indicates, please pick your battles carefully.