Testicular cancer (also referred to as testicular germ cell tumors or GCTs) is the most common solid malignancy in men between the ages of 15 and 34 years in the general population.
Studies assessing cancer incidence demonstrate that HIV-positive men are 1.4 to 8.2 times more likely to develop testicular cancer, though another study failed to show significantly increased incidence.
While no viral oncogene has been implicated in HIV-associated testicular cancer, viruses such as mumps orchitis, HPV, Epstein-Barr virus (EBV), and human endogenous retrovirus K10 are associated with testicular cancer in HIV-negative men and may be involved in development of testicular cancer in the HIV-positive population.
One large study reported a modest association between incidence of seminoma GCT and immunosuppression. However, another analysis showed that HIV-positive patients with seminoma appeared to have preserved immune systems.
In few words; there is a possibility that HIV patients are more prone to develop testicular cancer, in evidence base medicine.