Loyola researchers zero in on protein that destroys HIV

  • jay420

    Posts: 5

    Aug 26, 2010 3:31 AM GMT
    QUOTE AUTHOR GOES HEREUsing a $225,000 microscope, researchers have identified the key components of a protein called TRIM5a that destroys HIV in rhesus monkeys.

    The finding could lead to new TRIM5a-based treatments that would knock out HIV in humans, said senior researcher Edward M. Campbell, PhD, of Loyola University Health System.

    Campbell and colleagues report their findings in an article featured on the cover of the Sept. 15, 2010 issue of the journal Virology, now available online.

    In 2004, other researchers reported that TRIM5a protects rhesus monkeys from HIV. The TRIM5a protein first latches on to a HIV virus, then other TRIM5a proteins gang up and destroy the virus.

    Humans also have TRIM5a, but while the human version of TRIM5a protects against some viruses, it does not protect against HIV.

    Researchers hope to turn TRIM5a into an effective therapeutic agent. But first they need to identify the components in TRIM5a that enable the protein to destroy viruses. “Scientists have been trying to develop antiviral therapies for only about 75 years," Campbell said. "Evolution has been playing this game for millions of years, and it has identified a point of intervention that we still know very little about."


    http://www.loyolamedicine.org/News/News_Releases/news_release_detail.cfm?var_news_release_id=973441241
  • DrobUA

    Posts: 1331

    Aug 26, 2010 4:45 AM GMT
    Interesting..
  • Posted by a hidden member.
    Log in to view his profile

    Aug 26, 2010 4:51 AM GMT
    Interesting news. Just don't tell Pfizer or AstraZenecaicon_wink.gif
  • Posted by a hidden member.
    Log in to view his profile

    Aug 26, 2010 7:09 AM GMT
    Mostwant3d saidInteresting news. Just don't tell Pfizer or AstraZenecaicon_wink.gif


    Haha, well said. But isn't the phrase "nonprofit pharmaceutical"almost certainly an oxymoron?
  • Posted by a hidden member.
    Log in to view his profile

    Aug 26, 2010 10:25 AM GMT
    Cut to scene eight years from now:

    "Hi welcome to [insert-stupid-name-here]. What would you like?"

    "Um hiiiii, can I have the strawberry TRIM5a protein shake please?"