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GcMAf as treatment for HIV

  • mikey_101 Posts: 250
    QUOTE Apr 15, 2011 10:43 AM GMT
    I have been looking at the research relating to GcMAf as a reliable (but not orthodox or authorised by pharmacutical/medical) treatment for HIV.

    "Dr Yamamoto carefully selected his trials: he took fit people with in the early stages of cancer and HIV, and reported 100% success, with no recurrence after many years.

    HIV participants should expect to see viral loads drop to zero, and CD4 counts rise by at least 300 points in 16 weeks, and if that doesn't happen we will refund your money."

    http://www.gcmaf.eu/info/


    I just wondered if anyone else is aware of this treatment?

    I would love to hear first hand experience - this seems like a very simple method of 'curing' (yes - note, its in quotation!) HIV.

    Medical science and Pharmacutical industry seem to be surpressing this treatment - they would loose out on the massive profit from the expense of lifetime treatment and HIV medication.
    This treatment even comes with a money back guarantee....

    Any info or expericence would be appreciated.

    Thanks.
  • billybttm Posts: 14
    QUOTE Apr 15, 2011 6:49 PM GMT
    I started taking GcMAF in late March. I will be getting full blood work in early May so I should know in about 3 weeks if it is working for me.
  • Posted by a hidden member.Log in to view his profile
    QUOTE Apr 16, 2011 1:30 PM GMT
    Billy, please keep us posted. I'm always wary of anything promising 100% eradication.

  • jlly_rnchr Posts: 1758
    QUOTE Apr 16, 2011 2:10 PM GMT
    An HIV treatment comes with a money-back guarantee? Yeah, so does Proactive. This is odd.





    To those thinking there is a conspiracy, I ask why? If a researcher legitimately could cure HIV, I don't think he'd ever shut up about it. He's be instantly rich, famous, TIME Man of the Year, Nobel Prize winner, etc. So I honestly doubt this claim.

    Also, the other cure, which actually was a cure, was reported pretty quickly and in journals. http://en.wikipedia.org/wiki/CCR5#CCR5-.CE.9432. A bone marrow transplant with a donor who is homozygous for the CCR5-delta32 deletion is the only proven cure. I wouldn't believe much else.
  • Posted by a hidden member.Log in to view his profile
    QUOTE Apr 16, 2011 2:23 PM GMT
    It sounds hard to believe, but we have to have hope.

    Billy...please keep us posted. I am undetectable and healthy, but I am always hoping for more.
  • mikey_101 Posts: 250
    QUOTE Apr 18, 2011 9:03 AM GMT
    billybttm saidI started taking GcMAF in late March. I will be getting full blood work in early May so I should know in about 3 weeks if it is working for me.




    Thanks for your response Billy, I'm keeping my fingers crossed that this is a real option.

    Would you be so kind to keep us updated here?

    Thank you.
  • billybttm Posts: 14
    QUOTE Apr 18, 2011 3:27 PM GMT
    I'll do my best.

    I've spent the past nine months researching GcMAF. Yamamoto's work in this field goes back decades (he's 86 years old, in fact.) The theoretical underpinnings of what he's done are surprisingly solid, so those claiming that this "must be" a sham really need to step up to the plate and demonstrate some solid, reliable science that runs counter to what he's doing.

    I handed the 2009 Virology paper to my own HIV specialist. He was very interested at the time, but he hasn't mentioned it since then, except for the beginning of March when I asked him if he had any objection to me starting the protocol (which I'm doing with my naturopath as I trust her much more than the specialist.) He didn't object.

    It's difficult to obtain because the production method is covered by a patent (although the substance itself is not patented because it is naturally occuring.) I've been able to find four sources for it - one in the Bahamas (at a private clinic,) two in the Netherlands (I'm told, but have not confirmed, that this is due to the fact the US patent was not cross filed there,) and one in Israel (presumably licenced by Yamamoto himself to produce it.) I'm skeptical of private clinics in the Bahamas, and I've heard (indirectly) that the Israeli source is quite expensive. The two in the NL are comparably priced (at around 100 euros per dose) and at least one of them (gcmaf.eu) has published data indicating that their version is as potent as that used by Yamamoto himself.

    I've spoken with one other person who has started GcMAF for HIV as well and we do compare notes. In early May I will get my standard blood work and at that point I will have been on the protocol for over a month so then the results will be telling. I'm not on ARVs, with a CD4 count around 420 (30%,) and a viral load around 20k.

    If it is working, I would expect those numbers to change substantially after five weeks of full treatment (my last tests were done five days after I started the partial doses, so they aren't really definitive.) We shall see.

    A couple of other observations:

    - Yamamoto doesn't promise 100% eradication. He only reported 100% eradication in the patients he picked for his study. He WAS particular and DID screen people out. Thus, this isn't guaranteed to work for everyone (and there are reports of strong cases of IRIS in those that have been on ARVs for a while, but those are not the types of people Yamamoto picked for his trials.)

    - I don't think there's a conspiracy per se, but I do think the system as it is presently set up is not really conducive to developing a cure. An NDA application in the US is $1.5 million, plus the cost of actual trials. Because GcMAF is naturally occurring, it will be difficult for companies to recoup those costs. That discourages them from making the investment necessary to investigate it further, as it does not give them the kind of exclusive marketing arrangement they need to generate sufficient profits to justify the high risk investment.

    - I've been surprised at how much research there is on GcMAF - it's not as if this is a huge secret. But then again, there can be quite a delay between the time research is being done and the time that research is absorbed by industry. I couldn't understand why my own specialist didn't know anything about it (even though Yamamoto has been publishing papers about GcMAF and HIV since the mid-90s.)

    I'm up for my fourth full dose today. I have noticed some differences already (the most surprising of which was that a very low grade swelling in the lymph node on the right side of my jaw is gone. I'd had that for so long I no longer gave it any thought.) So it seems it's doing something. I'll find out next month if it is doing something useful.

  • mikey_101 Posts: 250
    QUOTE Apr 19, 2011 8:35 AM GMT
    Thanks for this Billy....

    I completely agree that there is no overt conspiracy - its all just down to money - what a sad world we live in... yet this still brings me hope.

    I'm pleased you managed to get your specialist to agree to the treatement. Do you have a link to the study you gave them?

    Also just wondering if you were previously on ARV's and stopped before starting GcMAF?
  • poznaund Posts: 1
    QUOTE Apr 19, 2011 3:42 PM GMT
    Hi guys,

    my name is jens from France. I am 34 and HIV+ since 2009.

    I study GC-MAF Treatment since more than a year and did much research on it.

    I take GC-MAF since 5 weeks now and I can tell you I am really fit and powerfull.

    My VL was before 3600c and my CD4 660 without any treatment.

    I will have a new bloodtest in May2011

    I wish you good health and all the best.

    Regards Jens

    PS: DO NOT ORDER IN ISRAEL!!!!
  • billybttm Posts: 14
    QUOTE Apr 20, 2011 4:06 AM GMT
    My only experience with ARVs is a course of PEP 8 years ago; it was not a pleasant experience. I was diagnosed late last summer as part of a mandatory physical examination and since that time have been dealing with the ramifications of my test results.

    Here is the link to the abstract and I've been able to get the full PDF version of this article as well (there's a link from the Wiley page): http://onlinelibrary.wiley.com/doi/10.1002/jmv.21376/abstract

    I came across this reference last fall and spent time researching it (along with other possible avenues for addressing the very serious repercussions this has caused for me personally.) The deeper I dug, the more it seemed that I'd discovered the culmination of nearly 30 years of work by a rather dedicated medical researcher.

    Of course, that doesn't mean it works, either. There was a presentation last summer in Vienna that discussed genetic predisposition to responding to GcMAF, for example, and it is highly effective for some, but not for everyone.

    Based upon my reading, you should not take [ARVs while on GcMAF (nor should you take most anything else, either, as apparently a number of drugs interfere with macrophage activation and there is inadequate research to indicate which drugs do and do not interfere at this point in time.)

    That GcMAF exists and causes macrophage activation seems well-established based upon my own reading of the literature as there are a fair number of papers discussing this issue. There are no published confirmations of Yamamoto's work as of yet, although there is an Italian researcher that claims to have reproduced it.

    I see Jens is also using himself as a guinea pig for GcMAF and I know of at least one other person using it for treatment as well.

    I see Jens discredited the Israeli version; I don't know much about this company and the only positive feedback I have seen is a post by an anonymous person claiming that he was taking it and getting tremendous results.

    The numbers in the paper are startling: of the five patients profiles detailed by Yamamoto, four of five had achieved undetectable viral loads within 6 weeks, all had observed substantially higher CD4 counts and substantially lower CD8 counts (indicating a reversal of the TH1->TH2 shift that occurs in HIV positive patients.)

    But Yamamoto's original work was done 10+ years ago now (he previously published the results.) The 2009 paper was a review paper - going back over the previous work and indicating that the 15 patients had not suffered a relapse in their condition in the seven years since the first paper.

    For me and in my personal situation, it seemed quite useful to take a risk and try GcMAF. I will share my results (I actually found this thread because I watch Google for this topic area. While I do Crossfit for my personal fitness, I certainly don't consider myself to be a "real jock.")

    I had my fourth full does yesterday. I've got two more doses between now and my next blood work. If it is doing the job, I should be able to see it on the next blood tests - but only time will tell.
  • mikey_101 Posts: 250
    QUOTE May 03, 2011 10:32 AM GMT
    Hi Billy -

    How are you getting on?
    Your blood results must be due soon?

    Please do keep us updated!


  • henson Posts: 4
    QUOTE May 03, 2011 4:07 PM GMT
    I was at the HIV congress in Florence and read a poster on GcMaf. The university team producing it had published a paper on a lady who used GC Maf from GcMAF.EU and had a 250 increase in her CD4 count and no viral load after ten weeks of GcMAF treatment.

    I spoke to this team and they told me that there were clinical trails underway in Europe and the results would be available late May.

    I contacted GCMAF.EU and they were aware of this trial and have other HIV and AIDS patients who have purchased their gcmaf and are self treating and feeding back their results to the site. They say they will post the clinical trial results on their website when they are available. I am watching that space hoping for positive results.
  • Posted by a hidden member.Log in to view his profile
    QUOTE May 04, 2011 7:52 AM GMT
    I don't trust any input from you faceless newbies pushing this thing, by the way. If you don't have a face, I can't see how untrustworthy you are.
  • henson Posts: 4
    QUOTE May 04, 2011 7:38 PM GMT
    Faceless untrustworthy newbie I may be, but at least I have bothered to do the research and recognise and embrace GcMAF's potential to restore an immune system to help fight the virus.
    My friend has just started taking it and should have some results soon.
    I for one will be watching the GcMAF website so see how their patients got on. My feeling is that this may be an important tool against the virus.
  • Posted by a hidden member.Log in to view his profile
    QUOTE May 04, 2011 11:32 PM GMT
    Everyone who is pushing GcMAF is talking about results they don't have yet..

    15 people is an extremely small sample for a drug test.

    There is only that initial study published in the Journal of Virology and in the study half of his work is self-referential..

    From a scientific viewpoint taking GcMAF is the equivillant of trying to hit the lottery.

    I hope it works for you guys, but they need a lot more testing before anyone is going to get behind this. If it works, someone is going to run with it I'm sure.
  • billybttm Posts: 14
    QUOTE May 07, 2011 3:26 PM GMT
    mikey_101 saidHi Billy -

    How are you getting on?
    Your blood results must be due soon?

    Please do keep us updated!




    Hi Mikey, I'll be getting my next round of results (standard blood panel - CD4/CD8, HIV-1 RNA, etc.) on Monday (May 9th.)

    I agree that a 15 person trial is small, but it's normal for a pre-clinical trial. What's unusual is to have positive response from all 15 people in such a trial - this indicates that the results are very unlikely to be random occurrence (certainly from a t-testing perspective.)
  • henson Posts: 4
    QUOTE May 08, 2011 10:28 PM GMT
    Your posts are excellent and accurate. I wish you well for your test results and hope they are positive.

    I too have been concerned about the 15 text book HIV recoveries. This just does not happen in real life.

    I know some self medicating gcmaf people and they do not all respond in the same way as the trial 15 were supposed to.

    They recover in different ways.

    My friend is having a rotten time at present and lab results not as predicted.
    We are sticking with this as there is no way apart from ARV which is life threatening, so still watching the space on their website.

    Test results for their trial will be within two weks and they say all results positive or bad will be published. Hope they mean what they sayicon_question.gif



  • mikey_101 Posts: 250
    QUOTE May 09, 2011 7:26 AM GMT
    Thanks for your input Henson.... do you have a link to the website you mention?

    Billy - please keep us posted on your results when you get them later today... good luck!
  • billybttm Posts: 14
    QUOTE May 09, 2011 11:05 PM GMT
    My results indicated no effect. CD4 was 400 (25%), HIV-1 RNA was 28k. This is after four weeks of GcMAF therapy. This does not match with the Yamamoto results (nor Ruggerio's confirmation of those results with the case described in late March,) so either the material I have is not the same, I am not responding in the same way that the original test subjects, or there is something else I've missed from the protocol.

    I have sufficient GcMAF to continue through mid-June, so I will certainly continue it at least to that point. Then I need to decide if I wish to stick with it for the full 18 week protocol, abandon it or try to use it from a different source (the latter particularly if others are meeting with success.)
  • mikey_101 Posts: 250
    QUOTE May 10, 2011 12:03 PM GMT
    Thanks for keeping us updated Billy - Im soprry there hasnt been a miraculus change just yet, but please keep the faith.... and keep us updated.

    I hope you get the response to the treatment that we hope for.
  • henson Posts: 4
    QUOTE May 11, 2011 5:27 PM GMT
    Hi Billy,
    Stick with it, you are only at week four so your immune system is in the early stages of its rebuild. The lady who recovered in the university poster presentation was taking GcMaf for ten weeks, then had her counts done at least 2 weeks later. Apparently this allows the immune sytem to settle down and then a true reading should be obtained.
    It is difficult to know if Gc Maf is the real deal. My friend is taking it and i asked him to purchase it from the website that had theirs independently tested. Even though I am certain that he has the real stuff, we both agree that we should try for 8 weeks (this is the amount of Gcmaf in our bottle) and then try for a blood test two weeks later. We are hoping for CD4 to increase.
    I am hoping it is working. He is not having a good time this week so I am on house work duty ;-(
    Keep us posted please Billy
  • QUOTE May 11, 2011 8:29 PM GMT
    I'll say this, I am skeptical, because their claims are defying my medical understanding and knowledge of HIV and Pharmacological therapy...

    However, modern science has always shunned what is not proven in hard facts...i.e. chiropractic care, massage, acupuncture, herbal remedies, etc...

    It's up to you, research it thoroughly, it's just the explanation they give on their website with macrophages and CD4 target cells, and treatments leaves loopholes in the explanation...
  • billybttm Posts: 14
    QUOTE May 19, 2011 9:30 PM GMT
    Many things work in ways that are clearly not understood, even when there is a theory of how they work.

    For example, ARVs are understood to suppress viral replication and improve health over an extended period of time, yet when very sick people take them they often rebound within days - that hardly fits the theoretical model. HIV specialists focus on CD4 and HIV-1 RNA levels, even though there's quite a body of evidence that they have only a weak correlation with prognosis (and yet they ignore glutathione and serum selenium levels that have been shown to have stronger correlations with prognosis. Go figure.)

    Or take statins - the evidence is that any benefit they have is the anti-inflammatory effect, not because they lower serum cholesterol (which of course makes little sense, given that cholesterol is used by the body to effect repairs.) But ask your doctor and you're likely to notice they focus on your serum cholesterol level.

    Even if this doesn't work, I don't plan on abandoning therapies that strengthen the immune system (e.g., intestinal health, another area with a growing body of evidence that it is critical to long term health, especially for HIV positive people.)
  • billybttm Posts: 14
    QUOTE Jun 07, 2011 3:17 AM GMT
    I've taken my 14th dose. I had blood drawn for more lab work last week. I also spoke to someone else using GcMAF and he received good news in that one of the tests from the original paper (nagalase) had dropped for him - so it seems to do something. What that means with respect to CD4 and VL isn't so clear, although I've heard a claim that most patients do not see a drop in those values a few weeks after the protocol ends.

    What this means is still not clear to me. I'm down to two more doses, so I have to decide if I want to continue the protocol. I'm hoping to have my lab results back this week so I can decide what I will do.
  • mikey_101 Posts: 250
    QUOTE Jun 07, 2011 12:02 PM GMT
    Thanks for keeping us updated Billy - please let us know how your blood results work out when you get them.

    I'm keeping my fingers crossed.


    Also - are you doing this treatment with the consent of your doctor?