Park in the Marina Green area near the Marina Safeway. Then run along GG Promenade to the GG Bridge, across the eastern sidewalk on the bridge to Vista Point, and back again. That's about 10 miles and spectacular.
The run on the Embarcadero is good. But if you get tired of urban running, GG Park has many, many trails, though I realize getting there maybe an issue.
Also, my running club has weekend runs in spectacular settings around the area...from 8 to 12 miles in length.
You can also email any of the officers (I'm one) to get more info on runs you might do depending upon where your hotel is.