I once fooled around with a guy that had no nuts. He had complications from undescended testicles as kid and lost them both. He was on HRT and had prosthetic nads and I would never have suspected if he hadn't told me about it. It made no difference, he was still cute and a great lay. One nut, two nuts, three nuts, no nuts, as long as everything else is in working order that's fine with me.
I almost lost one of mine about 8 years back from a severe case of epididymitis. Spooging blood all sorts of fun stuff. Since then it has atrophied to about 1/4 of it's original size. It would have sucked if I would have lost it completely, but I think i would have gotten over it. I think what is left of it doesn't work anyway.