U.S. Gamers Crack Puzzle in AIDS Research that Stumped Scientists for Years

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    Sep 21, 2011 1:06 PM GMT
    Pretty interesting article about the power of crowdsourcing. Scientists made the discovery of the protein into a game and let gamers help unravel it.

    Article Link
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    Sep 21, 2011 3:37 PM GMT
    Yeah, I saw that. Reminds me of the ESP game that was developed and later used by Google to label images by having people play a game of trying to guess what another person might be thinking about an image (hence ESP)

    http://en.wikipedia.org/wiki/ESP_game
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    Sep 21, 2011 3:59 PM GMT
    As a scientist, these developments are always fascinating to me. Very cool!
  • kietkat

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    Sep 21, 2011 4:12 PM GMT
    Very interesting use of Fold-It. As a chemist, Ive seen human intuition do amazing things; many of which are backed by latter experimental data. Love reading about unconventional developments in science.
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    Sep 21, 2011 4:25 PM GMT
    Sony tried something similar for cancer research with the PlayStation network, but it hasn't panned out. It's good to know things like this actually can and do work in the field.

    We need more of this.
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    Sep 21, 2011 4:25 PM GMT
    Not because I want to be an asshole (it's just an intrinsic character trait I have) but they probably could have solved it using the Rosetta molecular replacement function in Phenix. Rosetta is an energy minimization function also used in Foldit so I would expect some of the same results. And MR_rosetta, while new, is crazy good. It's like magic.
    Nice comments (also nicer than mine) on the paper here: http://pipeline.corante.com/archives/2011/09/20/foldit_notches_a_protein_structure_success_and_some_failures.php