Researchers Discover Method Of "Disarming" HIV

  • metta

    Posts: 39104

    Sep 22, 2011 8:32 PM GMT
    Researchers Discover Method Of "Disarming" HIV

    [QUOTE]
    Researchers from the United States and Europe working in laboratories on the human immunodeficiency virus (HIV) found it is unable to damage the immune system if cholesterol is removed from the virus's membrane.
    [/QUOTE]

    http://instinctmagazine.com/blogs/blog/researchers-discover-method-of-disarming-hiv


    [QUOTE]
    "HIV is very sneaky," Boasso said in a statement. "It evades the host's defenses by triggering overblown responses that damage the immune system. It's like revving your car in first gear for too long -- eventually the engine blows out.
    He said this may be why developing a vaccine has proven so tricky. "Most vaccines prime the adaptive response to recognize the invader, but it's hard for this to work if the virus triggers other mechanisms that weaken the adaptive response."
    HIV takes its membrane from the cell that it infects, the researchers explained in their study. This membrane contains cholesterol, which helps keep it fluid and enables it to interact with particular types of cell.
    Normally, a subset of immune cells called plasmacytoid dendritic cells (pDCs) recognize HIV quickly and react by producing signaling molecules called interferons. These signals activate various processes which are initially helpful, but which damage the immune system if switched on for too long.
    Working with scientists Johns Hopkins University, the University of Milan and Innsbruck University, Boasso's team found that if cholesterol is removed from HIV's envelope, it can no longer activate pDCs. As a result, T cells, which orchestrate the adaptive response, can fight the virus more effectively.
    [/QUOTE]

    http://news.yahoo.com/scientists-way-disarm-aids-virus-210805678.html
  • Posted by a hidden member.
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    Sep 22, 2011 8:58 PM GMT
    They made it less fatty?
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    Sep 22, 2011 10:00 PM GMT
    Does that mean that if I free-base fish oil and Lipotor, I'll be cured?

    Hot damn! Someone fetch me some rubber tubing, a can of sterno, a teaspoon and a dirty syringe!



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  • musicdude

    Posts: 734

    Sep 22, 2011 10:01 PM GMT
    makes sense. a skinny bitch is easier to takle than a fat football defensemen
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    Sep 22, 2011 10:04 PM GMT
    The_Guerrilla_Sodomite saidDoes that mean that if I free-base fish oil and Lipotor, I'll be cured?

    Hot damn! Someone fetch me some rubber tubing, a can of sterno, a teaspoon and a dirty syringe!



    Photobucket


    Sounds like a plot for a porno I'd probably watch.

    Or may already have.
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    Sep 22, 2011 10:06 PM GMT
    musicdude saidmakes sense. a skinny bitch is easier to takle than a fat football defensemen


    Haha Nice! icon_lol.gif

    Great news which could be a huge step forward in fighting HIV
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    Sep 22, 2011 10:06 PM GMT
    Trollileo said
    Inostrankan said
    The_Guerrilla_Sodomite saidDoes that mean that if I free-base fish oil and Lipotor, I'll be cured?

    Hot damn! Someone fetch me some rubber tubing, a can of sterno, a teaspoon and a dirty syringe!



    Photobucket


    Sounds like a plot for a porno I'd probably watch.

    Or may already have.
    I thought you starred in it?


    Or that.
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    Sep 22, 2011 11:30 PM GMT
    so does this mean that if everyone eats Cheerios morning noon and night, that our cholesterol will drop to nothing and we will starve HIV out of existence?
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    Sep 22, 2011 11:39 PM GMT
    The_Guerrilla_Sodomite saidDoes that mean that if I free-base fish oil and Lipotor, I'll be cured?

    Hot damn! Someone fetch me some rubber tubing, a can of sterno, a teaspoon and a dirty syringe!



    Photobucket


    Fetchiiiiiing! My only syringe is dirty with melted butter because I use it for spraying on popcorn. Is that going to be a problem here?

    Why would you want to tackle a skinny bitch? You'll just break us.
  • inuman

    Posts: 733

    Sep 22, 2011 11:45 PM GMT
    Awesome thread on both counts icon_razz.gif
  • Sparkycat

    Posts: 1064

    Sep 23, 2011 2:32 AM GMT
    how interesting....the number of silly, juvenile responses to what is important progress in the fight against HIV...
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    Sep 23, 2011 2:49 AM GMT
    Sparkycat saidhow interesting....the number of silly, juvenile responses to what is important progress in the fight against HIV...


    Oh, just fuck off and die already. I've had it for 13 years. If want to post a juvenile response, I'm gonna do it. So fuck you, fuck yo momma and fuck the horse you rode in on.


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    Sep 23, 2011 2:56 AM GMT
    The_Guerrilla_Sodomite said
    Sparkycat saidhow interesting....the number of silly, juvenile responses to what is important progress in the fight against HIV...


    Oh, just fuck off and die already. I've had it for 13 years. If want to post a juvenile response, I'm gonna do it. So fuck you, fuck yo momma and fuck the horse you rode in on.


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    Lawdy.

    You're my hero, GS icon_smile.gif
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    Sep 23, 2011 3:05 AM GMT
    It's interesting. I read about the discovery a couple of days ago. It sounds promising, but I don't understand how they can remove the cholesterol just from the HIV cells and not from all of the cells in your body, which would kill you. They'd have to find a way to target HIV cells specifically.
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    Sep 23, 2011 3:25 AM GMT
    GwgTrunks said
    The_Guerrilla_Sodomite said
    Sparkycat saidhow interesting....the number of silly, juvenile responses to what is important progress in the fight against HIV...


    Oh, just fuck off and die already. I've had it for 13 years. If want to post a juvenile response, I'm gonna do it. So fuck you, fuck yo momma and fuck the horse you rode in on.


    Photobucket


    Lawdy.

    You're my hero, GS icon_smile.gif


    Love ya back! icon_wink.gif
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    Sep 23, 2011 3:30 AM GMT
    Did you all see this article?

    http://www.cbsnews.com/8301-504763_162-20108763-10391704.html

    Video gamers solved an HIV protein puzzle in three weeks after scientists had been stumped for over a decade. They think that the discovery will lead to new and better drugs.
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    Sep 23, 2011 3:34 AM GMT
    DudeInNOVA saidDid you all see this article?

    http://www.cbsnews.com/8301-504763_162-20108763-10391704.html

    Video gamers solved an HIV protein puzzle in three weeks after scientists had been stumped for over a decade. They think that the discovery will lead to new and better drugs.


    Yup. Now that's some interesting stuff. http://www.realjock.com/gayforums/1825764
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    Sep 23, 2011 3:38 AM GMT
    Ah, I thought there might be a topic for it already. That's why I didn't create a new topic.
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    Sep 23, 2011 3:46 AM GMT
    11337S saidwasn't some german man already pretty much cured through bone marrow transplant quite some time ago?

    don't know word for word what it is that they did but the man hasn't shown any traces of hiv in about i think 5 yrs.. don't quote me on this so i hope u search it but one or the other, both mean the same thing to a lot of people..

    free-baking.



    You're thinking of this story, I think.

    http://www.time.com/time/health/article/0,8599,1858843,00.html

    According to the article, bone marrow transplants kill 1/3 of the patients, so it isn't a viable option.
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    Sep 23, 2011 5:30 AM GMT
    DudeInNOVA said
    11337S saidwasn't some german man already pretty much cured through bone marrow transplant quite some time ago?

    don't know word for word what it is that they did but the man hasn't shown any traces of hiv in about i think 5 yrs.. don't quote me on this so i hope u search it but one or the other, both mean the same thing to a lot of people..

    free-baking.



    You're thinking of this story, I think.

    http://www.time.com/time/health/article/0,8599,1858843,00.html

    According to the article, bone marrow transplants kill 1/3 of the patients, so it isn't a viable option.


    It was more of a happy accident than anything else. Just seeing what friends and family have gone through with chemo and radiation, let alone that AND a bone marrow transplant, I would opt to just keep taking my meds even if it was a viable solution.
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    Sep 23, 2011 6:05 AM GMT
    The_Guerrilla_Sodomite saidIt was more of a happy accident than anything else. Just seeing what friends and family have gone through with chemo and radiation, let alone that AND a bone marrow transplant, I would opt to just keep taking my meds even if it was a viable solution.


    Yeah, it's way to drastic a step to take to be realistic, but it does bring up the interesting question of how one person's immunity could be transferred to another. I think they've been looking at the question for a long time, but no one has been able to make it work. It sounds like the newer discoveries have a better chance of making a breakthrough.
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    Sep 23, 2011 3:16 PM GMT
    DudeInNOVA said
    The_Guerrilla_Sodomite saidIt was more of a happy accident than anything else. Just seeing what friends and family have gone through with chemo and radiation, let alone that AND a bone marrow transplant, I would opt to just keep taking my meds even if it was a viable solution.


    Yeah, it's way to drastic a step to take to be realistic, but it does bring up the interesting question of how one person's immunity could be transferred to another. I think they've been looking at the question for a long time, but no one has been able to make it work. It sounds like the newer discoveries have a better chance of making a breakthrough.


    You're right, and maybe the new mapping strategies might open other doors on what have until now been dead ends or accelerate work on current projects like the CCR5 based gene therapy.