Tweaking your genes for stronger, larger muscles...

  • He_Man

    Posts: 906

    Dec 20, 2011 6:36 PM GMT
    From Salk Institute's article:

    Tweaking a gene makes muscles twice as strong

    Salk scientists and their collaborators find new avenue for treating muscle degeneration in people who can't exercise

    November 18, 2011

    LA JOLLA, CA—An international team of scientists has created super-strong, high-endurance mice and worms by suppressing a natural muscle-growth inhibitor, suggesting treatments for age-related or genetics-related muscle degeneration are within reach.

    The project was a collaboration between researchers at the Salk Institute for Biological Studies, and two Swiss institutions, Ecole Polytechnique Federale de Lausanne (EPFL) and the University of Lausanne.

    The scientists found that a tiny inhibitor may be responsible for determining the strength of our muscles. By acting on a genome regulator (NCoR1), they were able to modulate the activity of certain genes, creating a strain of mighty mice whose muscles were twice a strong as those of normal mice.

    http://www.salk.edu/news/pressrelease_details.php?press_id=530


    Question:

    1) If you could undergo gene therapy to increase strength and muscle mass, would you do it?

    2) Who thinks this could lead to some kind of Super Soldier in the future?

    3) Could this be the new bodybuilding craze of the future?
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    Dec 20, 2011 7:03 PM GMT
    cure. fucking. cancer.
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    Dec 20, 2011 7:10 PM GMT
    YES! YES! YES!
    And YES to Cure Cancer First! icon_biggrin.gif
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    Dec 20, 2011 7:15 PM GMT
    Are there side effects? Yes?
    Then no, yes, maybe.
    No side effects?
    Then all of the above!!
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    Dec 20, 2011 7:18 PM GMT
    1) Hells yeah.

    2) I doubt it. Situations which necessitate biologically strong people aren't relevant to modern warfare. Hauling a gun so large only a genetic super soldier could carry it is nowhere near as practical as drone warfare or long range ballistics. Furthermore building and maintaining muscle is an expensive task even for just one person but when multiplied by an entire army the cost becomes insurmountable. Not only would quality healthy food need to be made, it would also have to be transported over great distances and stored in often extreme conditions.

    3) Absolutely, this along with studies into myostatin. I can't remember the quote exactly but a geneticist in the documentary Bigger, Faster, Stronger said something along the lines of "What we regard as talent will soon just be known as genetics."
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    Dec 20, 2011 7:28 PM GMT
    Peptides are already working in these areas...and there are many of them readily available.

    Some of the more interesting ones to come along are Follistatin, and Myostatin. A quick google search for "buying peptides" will show many different companies offering many different peptides. These are almost changing monthly as new compounds come along

    Tweaking what mother nature gave you is becoming easier.
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    Dec 20, 2011 11:45 PM GMT
    Captain America here we come.

    You can bet that as soon as it's out it will be used by all pro bodybuilders. I'm not so sure about the "super soldier" thing, is there precedence of the military using steroids before they were deemed illegal?
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    Dec 20, 2011 11:53 PM GMT
    OMG - is this how they made Captain America?????


    Ummm, hell yes, I would sign up.
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    Dec 21, 2011 12:00 AM GMT
    i would try it if it were safe and effective...but then again,it's probably best used in the medical field...for people who have muscle wasting disease..being the "best you can be"..should really be the result of hard work..not gene tweeking..Super Soldier..i doubt it..the trend today is away from individual soldier's battle prowess..more toward high tech precision weapons.a soldier with huge muscles is no more effective than a skinny one.an M16 or AK47 will rip thru muscle just as easy as cardboard..the gun changed warfare forever.
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    Dec 21, 2011 12:04 AM GMT
    VIIXIX saidPeptides are already working in these areas...and there are many of them readily available.

    Some of the more interesting ones to come along are Follistatin, and Myostatin. A quick google search for "buying peptides" will show many different companies offering many different peptides. These are almost changing monthly as new compounds come along

    Tweaking what mother nature gave you is becoming easier.


    Except that the peptides being sold are not the same as the ones used in the lab tests you read about. After a brief bit of googling it turns out that the people who have taken these market-available peptides are largely unhappy with the results.
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    Dec 21, 2011 12:06 AM GMT
    CuddleBuddy said
    LA JOLLA, CA—An international team of scientists has created super-strong, high-endurance mice and worms


    3318878274_212011b03f.jpg
  • E_84

    Posts: 201

    Dec 21, 2011 1:20 AM GMT
    The first thing that came to mind was Captain America.

    This new research is very interesting. In the bodybuilding world, a natural (to some point) alternative to steroids. This would be illegalized so fast against other unintended use as fitness/bodybuilding crazed individuals will seek this option. Natural Bodybuilders may actually have a procedure and still justify use as natural. Or is this natural? That would be an interesting debate. Very intrigued to see where this research will go.