Absolutely. The most important step is getting started, and forums like this exist in part for us to encourage and help each other toward fitness goals.
A few bits and pieces that come to mind, in no particular order:
-- Go slowly, and be patient. Don't resort to anything too extreme, and ignore the fad diets that call for eliminating any general category of food groups. You need a balanced and sensible diet that includes a wide variety of foods. Carbs are not evil. (I'm like a broken record on this, but it's true. We all NEED carbs, you just need to eat them in portions that don't drive your caloric intake above what you really need).
-- Try to find ways to integrate changes into your normal life. For example, I talked my aunt into putting her treadmill in the living room, so that she could watch TV while walking. This way she can get exercise without "punishing" herself and skipping something she enjoys to go lock herself in the basement.
-- Switch unhealthy snacks for healthier ones. Instead of ice cream or desserts high in refined sugars or fat, try having a bowl of breakfast cereal. Frosted mini wheats are an awesome substitute for potato chips. Fresh fruit, dried fruit, raw almonds, and yogurt (I prefer Greek style), are also good snacks... And you can enjoy them every few hours to keep yourself from getting overly hungry.
-- If you are integrating weight training into your routine, I recommend starting with some of the machines rather than free weights. Plenty of people are quick to recommend personal training, but since the vast majority of us are not Rockefellers (I know I could never afford a trainer on any regular basis), you can often learn a lot just by asking questions.
-- If you are joining a commercial gym, don't let yourself be intimidated by people who are at more advanced fitness levels. Gyms exist for all of us to use, and anyone who would criticize or think negatively of someone who is just starting out doesn't have the maturity to be there themselves. The important thing is making the effort, and being there.
Feel free to keep posting if you have more questions - that's what we are here for.