CDC Warns Untreatable Gonorrhea is On the Way

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    Feb 14, 2012 5:25 PM GMT
    http://www.usnews.com/news/articles/2012/02/13/cdc-warns-untreatable-gonorrhea-is-on-the-way

    A new strain of gonorrhea is resistant to one of the last known effective treatments [...]

    According to the CDC, gonorrhea has a long history of developing immunity to antibiotics, but doctors have always had a stronger medicine up their sleeves to treat patients. Not anymore—about 1.7 percent of gonorrhea is now resistant to cephalosporins, the last line of defense against gonorrhea. That might not seem like much, but it's a 17-fold increase since 2006, when about one tenth of one percent of gonorrhea was believed to have resistance to cephalosporins.

    According to Bolan, the strains are showing up most often in the western states, where 3.6 percent of gonorrhea has shown resistance to cephalosporins, and in men who have sex with men, with nearly 5 percent of gonorrhea showing resistance.

    The disease has been estimated to affect 600,000 Americans annually, causing burning with urination, abdominal pain, itching, and genital discharge.

    Nikki Mayes, a spokesperson for the CDC, wrote in an email that by using a combination of cephalosporins and other antibiotics, American doctors have been able to prevent anyone from getting a completely untreatable case of gonorrhea. But she says it's only a matter of time.


  • musclmed

    Posts: 3287

    Feb 16, 2012 1:28 AM GMT
    This is not the bogyman, this is the real deal.

    Higher dose and multiple day dosing can help.

    In our location a best practice is either IM Ceftriaxone plus Azithromycin or Doxycyline. We also give 500mg instead of 250mg of Ceftriaxone.

    Oral Cefixime x7 days provided the patient returns for culture.

    We had been doing the dual coverage for some time, given our patient demographic.

    We also do not treat oral or urogenital gonorrhea with oral medications alone, that is complicated in nature.

    Spectinomycin IM is approved outside of the US, and awaits FDA approval if needed.