Great suggestions above! Just a few more resources/suggestions to supplement. Last time I was at the Eagle, it seemed more like a Bear bar than a leather bar - maybe because it was the beer bust on Sunday... some hot, hairy men, if you're into it. http://sanfrancisco.gaycities.com/bars/44-the-eagle-tavern
See below in the "neighborhoods section" for other gay bars/clubs. Have a great trip!
EVENTS CALENDAR: http://www.sfstation.com/
Kind of a hippish collection of things to gander if you have the time.
sometimes handy in terms of what floats locals' boats in all things consumable (and free!)
FIRST THURSDAY: If you're into the art scene, the first Thursday of every month (August 7th if either of you are there) is a free opening of art galleries in downtown SF, often with free booze and finger foods. Check out this URL for a listing of galleries and locations: http://art-collecting.com/galleries_ca_sanfrancisco.htm
RESTAURANTS: If you're into really high-end restaurants, Gary Danko's is great and renowned: http://www.garydanko.com/
as is Campton Place, at least in 2005: [url]http://www.tajhotels.com/FoodandWine/Campton Place,SAN FRANCISCO/CAMPTON PLACE RESTAURANT/default.htm[/url] I've never been, but this place has always sounded intriguing: http://www.supperclub.com/
Check out yelp.com
for lots and lots of other suggestions.
NEIGHBORHOODS: 1) North Beach, China Town; 2) SOMA (http://sanfrancisco.gaycities.com/bars/nid/106/
), Mission, Castro. Each set of neighborhoods are close to each other so you could explore around both fairly readily.
STERN GROVE: Free concerts every weekend. http://www.sterngrove.org/07272008.html
DAY TRIPS: Marin Headlands for a hike (http://www.nps.gov/muwo/
), dinner at the Buckeye Roadhouse (http://www.buckeyeroadhouse.com/
), or beer and bangers at the Pelican Inn (http://www.pelicaninn.com/dining.html
); Napa/Sonoma Valleys, if you like wine (ZD, Rosenblum, Matanzas Creek are all great). Great restaurants up that way, too! (e.g. Cyrus, Red's, Bouchon, French Laundry ("best in the nation" according to some!). Half Moon Bay for a hike at Purisima Creek, and great sushi at Sushi Main Street (http://www.sushimainstreet.com/