You can stay at the Royal Palms, yes, but right by there is also the Flamingo (www.theflamingoresort.com) which is nice too and costs a little less. Those two are the bomb and both 5 star. And for a really good deal and a place next to the beach, you may want to check out The Alhambra Beach Resort (alhambrabeachresort.com ).
All are within a couple blocks of each other and all are gay resorts with nice pools, close to the beach, etc. The Alhambra is the best deal. The Royal Palms and the Flamingo have a little extra "fluff" but if you don't need your bath towels to be egyptian cotton, then go with the Alhambra, LOL. The money you save can be spent having fun elsewhere. Besides, having fun in Ft. Lauderdale is about NOT being in your hotel room.
If you want to go to clubs...hmmmm...I hope you have a rental car or a friend there. They are scattered all over the city. Most traveled clubs are Georgie's Alibi, The Colloseum, The Copa, Boom, Eagle, RamRod, and the like, (the names have probably changed by now - so ask). Any hotel is going to have "HotSpots" magazine or something like that in the lobby or you can ask for it and it will have all the places to go in "a gay way" in Fort Lahdeedah. Don't be affraid to ask..after all..it's Ft. Lauderdale. Many of the clubs change names so fast it will make your head spin, so it is VERY helpful to get the latest HotSpots Magazine or a gay guide mag. like it at your hotel.
If you want an excellent martini and great food where the gentlemen go and civilized setting, then I would go to "the Gin Mill"/Costello's near Georgie's Alibi and Boom. (remember...some of the clubs open up extra areas for more fun and dancing after 9 or 10 pm, so when you walk into a place in the early evening and think "that's it?!"...wait for it. LOL. Always ask the bartender if they have and "additional area" that opens up later, and at what time, or when does the fun start? They'll let you know.
You will also want to set aside an evening to stroll along Las Olas Blvd. - a street filled with the beautiful people, restaurants, boutiques, and very nice in the eveninigs all lit up. On Las Olas, after you've done some site seeing, strolled the street, and had dinner, walk over to Cathode Ray (also gay) and have some drinks and dancing. Fun Place. At any of the clubs, if they aren't hopping when you go in, ask where the fun is, as each place has it's special day and time...they will be happy to help you out.
When you are starving after that LONG night out on the town, go the The Floridian on Las Olas and have some great food - all the boys go there for chow.
Most importantly, where ever you will be staying, talk to the guys working there or the owners - usually one in the same, and tell them what you are in the mood for...dancing, or a popular watering hole, or shopping, a gay bar with lap dances, lol, etc., they will hook you up.
Oh...also, a nice place to check out is River Walk (afternoon or early evening) (the end of Las Olas Blvd.near downtown). Nice outdoor shopping and restaurant area and you can also hop on a boat and take a cruise around the waterways and the intercostal waterway for a pretty small/decent fee.
Near River Walk is Voo Doo Lounge - check and see if they have something cool going on while your there too.(I'm sure they will have a Labor Day Weekend party there at some point). They have some fun special events there.
Depending on what part of town you are staying in I would say that your two best "starting off" places with regard to clubs and getting the low down on what's going on where...would be either Cathode Ray on Las Olas ( www.cathoderayusa.com ) or Georgie's Alibi in Wilton Manors (http://georgiesalibi.com/wiltonmanors.html)
That'll get you started...good luck ! Take some aspirin, cuz those guys down there will wear you out ! I know, I used to live there. LOL.
HOTSPOTS MAGAZINE - http://www.hotspotsmagazine.com/index.cfm