Transfusion of young blood could delay onset of diseases like Alzheimer's

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    Oct 18, 2012 6:02 PM GMT
    Just in time for Halloween.

    http://www.telegraph.co.uk/health/9615779/Transfusion-of-young-blood-could-delay-onset-of-diseases-like-Alzheimers.html

    Giving middle-aged people a transfusion of young blood could keep their brain healthy in old age and delay the onset of diseases like Alzheimer's, scientists claim.

    Changes in the composition of our blood as we age may cause the deterioration of memory and other brain functions by damaging connections in the brain.

    Filtering younger blood into an older body could combat the problem by rejuvinating old tissue and keeping nerve cells in good working order, according to a new study.

    It means people in their 40s or 50s could in future be given blood donated by someone in their early twenties to prevent their brain from deteriorating and stave off diseases like Alzheimer's.

    Researchers from Stanford University found that old mice given transfusions of younger blood performed better in a memory task than those left to age naturally.

    They also began to re-grow connections in their brains which had previously begun to disappear as part of the aging process and which affect memory.
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    Oct 18, 2012 6:53 PM GMT
    Bring it on!!! icon_smile.gif
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    Oct 18, 2012 8:47 PM GMT
    51eSsIqBx5L._SL500_AA300_.jpg
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    Oct 18, 2012 8:48 PM GMT
    Exercise, bitches.
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    Oct 18, 2012 9:23 PM GMT
    I guess vampires had it right all along. Drink other people's blood and stay "alive." icon_biggrin.gif
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    Oct 18, 2012 9:24 PM GMT
    LET THE AGE OF VAMPIRES BEGIN! BWAHAHAHAHAHA!!!!!!
  • Dominican_Gen...

    Posts: 379

    Oct 18, 2012 10:30 PM GMT
    Creeeeeepy, but (if true) a medical breakthrough nonetheless.
  • Medjai

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    Oct 18, 2012 10:45 PM GMT
    I don't see how fresh blood would help remove beta-amyloid peptide plaques from within neurons, but okay...
  • red_series

    Posts: 136

    Oct 18, 2012 10:51 PM GMT
    Medjai saidI don't see how fresh blood would help remove beta-amyloid peptide plaques from within neurons, but okay...


    I think it's meant to be preventative
  • Medjai

    Posts: 2671

    Oct 18, 2012 10:53 PM GMT
    red_series said
    Medjai saidI don't see how fresh blood would help remove beta-amyloid peptide plaques from within neurons, but okay...


    I think it's meant to be preventative


    Either way. Removing intracellular plaques with young blood before or after they're a problem doesn't make sense to me. If the plaques were circulatory it'd make sense, but they aren't...
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    Oct 18, 2012 11:03 PM GMT
    Medjai said
    red_series said
    Medjai saidI don't see how fresh blood would help remove beta-amyloid peptide plaques from within neurons, but okay...


    I think it's meant to be preventative


    Either way. Removing intracellular plaques with young blood before or after they're a problem doesn't make sense to me. If the plaques were circulatory it'd make sense, but they aren't...



    I have to agree with Medjai

    Beta-amyloid is released into the brain every time a brain cell ruptures/dies. From birth every head injury or trauma ; or inhalation/ingestion of a brain damaging substance; or neural trauma such as stroke or seizure, will cause a brain cell to die thus releasing beta-amyloid.

    The body has no natural way of removing the beta-amyloid from the interstitial spaces withing the brain.

    the only way I can see of this as a working prevetative is if the "young blood" is better capable of assisting the O2/CO2 gas exchange rather than the geriatric persons native blood thus allowing for proper health and maintenance of the brain cells preventing their death and in the end prevent release of beta-amyloid
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    Oct 18, 2012 11:54 PM GMT
    suzanne somers
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    Oct 19, 2012 12:03 AM GMT
    This is almost certainly a humoral effect. I.e. blood-brain barrier precludes blood cells from penetrating the CSF.
    Sensitization to blood cell antigens is a no-no for transplant.
    Isolate that factor(s) that the young blood has that the older blood's lacking. Alternatively, eliminate the factor(s) that the older blood has that is damaging brain cells. (have they done the obvious follow-up experiment--transfuse older blood into younger animals?)
  • booboolv

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    Oct 19, 2012 9:38 AM GMT
    I'm in. All you young dudes line up and help an old fella out, would you? icon_wink.gif
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    Oct 19, 2012 8:44 PM GMT
    Outstanding!

    Finally a use for young people!

    Now if only we could find a use for old people!
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    Oct 19, 2012 8:48 PM GMT
    lilTanker saidOutstanding!

    Finally a use for young people!

    Now if only we could find a use for old people!



    LilTanker.... YOU ARE AWESOME!!!!
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    Oct 19, 2012 9:12 PM GMT
    lilTanker saidOutstanding!

    Finally a use for young people!

    Now if only we could find a use for old people!


    they need say alive to get old so they can be useful to younger ones.
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    Oct 19, 2012 9:32 PM GMT
    I believe the time has come for me to harvest my own blood, whilst i'm still young, fit and healthy, freeze it in satchels (garden shed freezer perhaps), and have these supplies ready for use in my old age, or unexpected ill health/injury, as and when I need a health boost.



    .......................(^^')<<------ My head: thinking
    [] <<--- BOX.... ^
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    Oct 19, 2012 9:43 PM GMT
    Trollileo said...I've thought of doing the same thing. I'm O-neg so when I get hit by a bus I'm pretty much fucked.


    I hear you.

    I think that there are likely many other health benefits to this that science hasn't yet even fully discovered.

    HIV, for example, has been cured in a handful of people who have had a sucessful BMT, blood transfusion, both from donors with and WITHOUTicon_biggrin.gificon_eek.gif the CCR5, HIV resistant gene .

    http://www.realjock.com/gayforums/2452127

    I'd bet this method will be found to have many other potential benefits in years to come.
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    Oct 19, 2012 9:44 PM GMT
    I'm almost embarressed to admit that at nearly the age of 25, I still don't know what my blood type is icon_redface.gif


    I hope it's anomalous and alien.