I think it depends on what you and your hook-up are looking to get out of it. It might also depend on what it takes for you to get sexual with someone. In my opinion, the most important thing is making sure you both are on the same page considering these factors. If you're looking for sex and only sex, then I think that minimal conversation is the best way to go. Once you show up, or he shows up, a simple cue to get things started (e.g., "are you cool with us just getting started?" or however you can articulate that you're ready for the fun to begin in the least awkward manner!) should be sufficient. When things are done, you can give another gentle cue to wrap things up generally works. If you guys have spoken for a while or you are each open to the possibility of your hook up developing into something more, then you could start with conversation before the hook up or end the hook up with some talking/hanging out.
A few other things that come to mind is that I always appreciate it when hosts don't make me feel trapped in their home or when travelers don't overstay their welcome. Also, the hospitality of hosts goes a long way for me too! And finally, I think hook ups are only as awkward as the people make it. So if you just be yourself and act friendly, then you should be fine!