From the first episode I found Golden Girls to be smarmy and distasteful - worse than South Park (which is my guilty pleasure). I really don't want to watch senior citizens (and I'll be one in ten years) making slutty double entendres about sex.
Designing Women was a favorite for a few seasons, then the attraction faded - as with many series, it's fun to compare the early episodes with the later. For instance, at the beginning Annie Potts was plain housewife material, with "small" hair and lots of sweaters. Over time she got "fancy" like the other gals. More to the point, DW was very forward about taking on gay issues - in particular the episode about their friend, a decorator with Aids. I recall a great episode about sex education, too.
On Will and Grace, Karen was and is my favorite. I can still catch a rerun and end up emailing her remarks to a friend.
As to Ab-Fab - so great, and I'm thankful that Roseanne's plan to star in a US version never came off. The one-and-only is just the best. I recall Jennifer Saunders saying once that the reason the characters kept becoming less and less redeemable was that fans kept saying they "liked or admired" them - YOU'RE NOT SUPPOSED TO ADMIRE THEM! she said.
To that end: the day of Sapphie's (forgotten) birthday, Eddie screamed at her sad daughter, "I'm sorry if I seem selfish, darling, but it's me, Me, ME!!!"