I'm new to this site, so if I mess up please forgive me. Four months ago I was put on testosterone therapy because mine was low. I am on a compound testosterone, the jar from the pharmacy says its 5% testosterone gel, 120 GM, I take Two 1/8 teaspoons daily, once in the morning and once before bed. Below is my recent lab results on that therapy. My testosterone is higher than the normal range. My question is: I have heard allot about guys with high testosterone being susceptible to strokes and heart attacks. Is my level too high? Although I love the pump I feel at the gym and like the quick results I'm seeing, I don't want my testosterone to be so high that it puts my life at risk. I have not gone back to my doctor, honestly I don't think he knows what he's doing.
My lab results:
Total testosterone - 10.5 High ng/mL Range - 2.2 - 8.4
Free testosterone - 18.82 pg/mL Range - 7.30-25.00
TSH - 1.110 ulU/mL Range - 0.358-3.740
Please advise. Thank you !!
Your tsh (thyroid stimulating hormone) is in the mid range of normal. It could maybe be up a bit. You can research this yourself, further. There some benefits to fine tuning your tsh, mainly, metabolic efficiency.
Free test is generally your guide, which..you're in normal.
Your lipid panel should be what you're paying closer attention to. Tamoxifen is well known for improving lipid panels for folks using exogenous testosterone. Depending on how knowledgeable your medical help is, you may, or may not, get good guidance there.
Taking adrogens will generally lower both your LDL, and HDL. You'll want fish oil, flaxseed oil, krill oil, olive oil, almond butter, peanut butter, nuts, avacodos, etc. (good polys and monos).
The real danger is the testosterone is more the estrogen to testosterone ratio, and your lipid panel
Decades of HRT research with HIV patients have shown remarkably improved outcomes with those patients on HRT, and there's a long list of benefits. That's why the FDA didn't hesitate to approve another topical testosterone formulation this week.
It used to be said that test caused prostate cancer. Not true. It's the ratio of estrogen to test. E2 gets too high. Higher DHT can cause some benign prostate enlargement and accelerated baldness (you can't go bald without the gene, and DHT just speeds it up). We now know that PSA tests really don't have the value that was once that, as more correlations have been drawn deeper down in research.
Someone who knows what they are doing will know how to mitigate bad effects.
For most, including me, the benefits of HRT far outway risk factors.
There's a strong body of evidence that many of the diseases of aging are because the E2 is too high relative to free T.
Beware of statins. While they'll lower your LDL, they'll kill your CK levels (well, put them over the top), and greatly impair your ability for muscular recovery. In my own case, I am not on any statins because they run my CK off the chart, and cause all sorts of muscle issues. Although drug marketing would have you believe otherwise, for an active person, with a good diet, THEY ARE ILL ADVISED, and will hinder your exercise performance and recovery, as well as up your risk of some other mortalities.
In long term studies with HIV patients, medical outcomes are markedly IMPROVED with HRT.
It can add years to your life, and allow you to continue to exercise at a level to keep your heart and body healthy. In general, the risks are easily mitigated via proper diet, and tamoxifen (not statins, which are highly bad for anyone active). There's a much lower risk of diseases of aging with HRT. Main thing is the lipid panel. As your test comes up, your cholesterol (steroids are cholesterol in nature) numbers are going to change. That HDL is going to be lowered (because it's being used), and, usually, the LDL will come down with it.
I've had a whole team of top of the industry folks that I've worked with on all this. Don't buy into some 2 minute package on a tv news show.
Additionally, you need to make sure you CMP and CBC is fine. It should be, but, if your hematocrit, or your RBC, get too high, you'll want to make changes. You should be watching the CMP, and CBC, anyway, to detect early issues with other disease.
As a matter of good practice, you should be taking 81mcg of aspirin daily as part of a heart healthy regimen (unless it's medically contra-indicated via a allergy or your ability to convert the aspirin).
Testosterone is good medicine.
My lipid panel is 100/38, FYI. Could be higher on the HDL, and sometimes I can get it higher, but, it reguires me really making sure I get more good fat. I'm considered at zero risk of heart disease because of my lipid panel ratio. Few folks will have a LDL below 100, and that's very good.
Tamoxifen is very commonly sold as a research chemical. You can research its benefits online.
Finally, as your E2 (estrogen) comes up, you retain more fluid, which, may mean your bp will come up. You need to check it.
In case you don't know it: testosterone breaks down into DHT, and estrogen (another steroid). DHT promotes what's called anabolic wellness (a sense of well being). Estrogen has lots of good benefits (immunity and lipid panel, as well as libido (yes, via the HPTTA circuit / HPT axis (excuse me if I miss a letter here))), but, too much in ratio to test can cause issues.
A well informed endocrinologist who has worked with active folks will know all this. He'll tell you basically what I told you and have you throw the statins in the trash. The PT will have you ditch the statins, too.