Aging Successfully Reversed in Mice; Human Trials to Begin Next

  • Posted by a hidden member.
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    Mar 31, 2014 8:11 AM GMT
    http://guardianlv.com/2014/01/ageing-successfully-reversed-in-mice-human-trials-to-begin-next/


    Thoughts?
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    Apr 02, 2014 7:40 PM GMT
    Sounds like more of your ageism bullshit
  • britmed

    Posts: 25

    Apr 16, 2014 2:11 PM GMT
    It's not actually bullshit research though anti-ageing may be a misnomer. IIRC the guy who carried out the original research had his publication and mechanistic theory (something to do with NAD+ regeneration) criticised. They recently found out it's true.

    This stuff won't make you live forever, but could improve old age morbidity by reducing muscular atrophy.
  • Posted by a hidden member.
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    Apr 16, 2014 2:17 PM GMT
    britmed saidIt's not actually bullshit research though anti-ageing may be a misnomer. IIRC the guy who carried out the original research had his publication and mechanistic theory (something to do with NAD+ regeneration) criticised. They recently found out it's true.

    This stuff won't make you live forever, but could improve old age morbidity by reducing muscular atrophy.


    Finally, someone smart here. icon_biggrin.gif
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    May 01, 2014 11:30 AM GMT
    Yes, it reversed inflammation and muscular atrophy.
    So, only certain aspects of aging.

    I understand that any study (especially those conducted on mice) need to be replicated , especially in humans, but dismissing it as BS is also premature.

    I have accumulated some knowledge on this topic by studying scientific literature, sharing it:

    NAD+ can be increased by taking supplements such as Nicotinamide Riboside. Also, CD38 inhibition can also help increase NAD+. CD38 inhibition is achieved by stuff such as C3G (present in blackberries) , luteolin and some other compounds. You can take supplements but bio-availability is a major issue. Also, dosage matters and one has to maintain levels through out the day as some of these compounds have a half life of a few hours.
  • Posted by a hidden member.
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    May 01, 2014 1:13 PM GMT
    karan_karan saidYes, it reversed inflammation and muscular atrophy.
    So, only certain aspects of aging.

    I understand that any study (especially those conducted on mice) need to be replicated , especially in humans, but dismissing it as BS is also premature.

    I have accumulated some knowledge on this topic by studying scientific literature, sharing it:

    NAD+ can be increased by taking supplements such as Nicotinamide Riboside. Also, CD38 inhibition can also help increase NAD+. CD38 inhibition is achieved by stuff such as C3G (present in blackberries) , luteolin and some other compounds. You can take supplements but bio-availability is a major issue. Also, dosage matters and one has to maintain levels through out the day as some of these compounds have a half life of a few hours.


    I think he was dismissing the OP because more than half his posts have to do with age. He's absolutely obsessed with age.
  • Posted by a hidden member.
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    May 01, 2014 3:51 PM GMT
    Good.

    I will be young forever..........

    Now I have more time to take over the world.