Researchers Discover Aggressive New HIV Strain In Cuba

  • AMoonHawk

    Posts: 11406

    Feb 16, 2015 5:27 AM GMT
    http://www.thegailygrind.com/2015/02/15/researchers-discover-aggressive-new-hiv-strain-cuba/

    "Researchers have discovered a new HIV strain in some patients in Cuba which appears to be much more aggressive and can develop into AIDS within three years of infection. Most alarmingly, the progression occurs so fast that treatment with antiretroviral drugs may come too late for some patients ... "
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    Feb 16, 2015 3:41 PM GMT
    Lol, that's why Obama must want to set up trade with cuba.
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    Feb 16, 2015 8:35 PM GMT
    Doesn't Cuba isolate all their patients who have HIV.

    It could be those same HIV patients have crossed strains so many times that a super strain was developed.
  • honestsweat

    Posts: 182

    Feb 16, 2015 8:42 PM GMT
    There goes the tourism industry.
  • Svnw688

    Posts: 3350

    Feb 17, 2015 5:02 PM GMT
    "A recombination of 3 variant HIV subtypes"

    Translation:

    HIV positive individuals (like ALL individuals) have a moral duty to NOT bareback with impunity. We've known since the 80s that an HIV+ individual can acquire additional strands, which can cause deleterious effects to that individual's health. And recombinations affecting the "herd" (aka, everyone else alive and yet to be born).

    And here we are.
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    Feb 17, 2015 7:25 PM GMT
    canadian_stud saidDoesn't Cuba isolate all their patients who have HIV.
    It could be those same HIV patients have crossed strains so many times that a super strain was developed.

    I was thinking the same thing about HIV+ people in Cuba. I think they have something like a leper colony for them.

    They probably get no advice or direction, no condoms, and are simply left to their own devices.

    Talk about stewing in your own juices.
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    Feb 17, 2015 11:38 PM GMT
    It's odd from a country such as Cuba.

    Keeping AIDS at Bay in Cuba

    31 July 2013

    Cuba boasts the lowest rates of HIV/AIDS in the Caribbean—if not the world. Should the credit go to the country’s early, internationally condemned policies aimed at stemming the spread of the disease?

    And what’s in store for this island nation now that its borders may reopen to Americans? Bill Strubbe and Karen Wald report


    http://www.cuba-solidarity.org.uk/cubasi_article.asp?ArticleID=157

    Yet, they had a condom shortage???

    Now, Cuba’s remarkable achievements in keeping HIV/AIDS rates low—admittedly by unethical means, at times—are now imperiled, not by a dearth of advanced medical treatment (Cuba produces its own antiretrovirals), but because of a scarcity of the most basic and inexpensive sexual health product.

    http://www.slate.com/blogs/the_world_/2014/04/23/cuba_s_condom_shortage_puts_its_low_hiv_levels_at_risk.html

    If they make their own (cheap) antivirals, what are they???

    Conclusions:
    Our study found a high prevalence of drug resistance and supports the need for appropriate laboratory monitoring in clinical practice and access to drug options in case of virological failure.

    http://www.jiasociety.org/index.php/jias/article/view/19754/html

    POZ Cubans have a high level of adherence. there shouldn't be a high prevalence of drug resistance.

    Where did this new strain come from? They isolate HIV patients. If they are so desperate they relabel expiration dates on condoms, how poorly and cheaply made are the antivirals?

    Something is amiss here!
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    Feb 17, 2015 11:57 PM GMT
    Damned Commie HIV. Can't trust any of them.
  • Apparition

    Posts: 3525

    Feb 18, 2015 10:18 PM GMT
    that sux

    but if there is anything out of bad situation, is that a faster disease is actually going to peter out faster than a slow one in a general population. not good for them, but good for the herd.
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    Feb 18, 2015 11:31 PM GMT
    Apparition saidthat sux

    but if there is anything out of bad situation, is that a faster disease is actually going to peter out faster than a slow one in a general population. not good for them, but good for the herd.


    Yes, that's not a very "smart" virus! The purpose of any organism is to live.

    It's all the more reason to get tested often. Supposedly the POZ population is very small (but doesn't Iraq say the same thing?), it could be a few isolated cases from Angola where there are other strains already.
  • conservativej...

    Posts: 2465

    Feb 18, 2015 11:37 PM GMT
    it has been known for some time that the diversity of HIV-1 in Cuba was similar to what you see in Central Africa, especially in Angola. As recombinant forms of the virus develop from this diverse base, odds increase that a few of the new strains are going to possess increased efficacy in producing full blown AIDS. That is what is occurring in Cuba.

    It is unfortunate that one of the blessings -- and I say that being sarcastic -- is that America's recent overtures towards Cuba may very well bring this new menace onto U.S. shores.
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    Feb 19, 2015 12:21 AM GMT
    conservativejock saidit has been known for some time that the diversity of HIV-1 in Cuba was similar to what you see in Central Africa, especially in Angola. As recombinant forms of the virus develop from this diverse base, odds increase that a few of the new strains are going to possess increased efficacy in producing full blown AIDS. That is what is occurring in Cuba.

    It is unfortunate that one of the blessings -- and I say that being sarcastic -- is that America's recent overtures towards Cuba may very well bring this new menace onto U.S. shores.


    If Cuba does have them ummmm 'under control' as they say, it shouldn't be much of a problem for the US.

    "Improved HIV drugs

    To this end, local authorities this year will begin implementing a package of changes to the antiretroviral treatment protocol. The undertaking aims to get very toxic drugs taken out of circulation, such as Indinavir and Nelfinavir, which include among their side effects lipodystrophy, the degeneration or loss of fatty tissue all over or on certain parts of the body

    This finding agrees with information published in The Gap Report, which indicates that there were more new diagnoses of HIV in Cuba in 2013 than in 2005, in contrast to the rest of the worst-affected nations in the Caribbean isles."


    http://www.keycorrespondents.org/2014/11/28/cuba-reforms-its-hiv-treatment-protocol/

    Cuba has been using re-labeled condoms, out dated medicine, experiencing drug resistance, and an INCREASE in HIV. And the new strain.

    I think Cuba is lying about their low numbers and drug availability. None of this should be happening. Many African countries have dramatically reduced new HIV infections, Why would Cuba have an increase with such a small population? If anything they should be close to eradicating it.

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    Feb 19, 2015 2:00 PM GMT
    AMoonHawk saidhttp://www.thegailygrind.com/2015/02/15/researchers-discover-aggressive-new-hiv-strain-cuba/

    "Researchers have discovered a new HIV strain in some patients in Cuba which appears to be much more aggressive and can develop into AIDS within three years of infection. Most alarmingly, the progression occurs so fast that treatment with antiretroviral drugs may come too late for some patients ... "


    Well I suppose that Cuba can simply put those infected on a boat and ship them to Florida.
  • Svnw688

    Posts: 3350

    Feb 19, 2015 3:55 PM GMT
    So, not to chicken little, but what's the upshot of this?

    IF this "gets out" to the larger global community, we'll see dying in the streets like we did in the 80s because meds, effectively, won't work and it'll be like the days BEFORE we had these life-extending drugs?

    And this was caused because a poor country, produced ghetto and bootleg drugs?

    And this in conjunction with the impending drug resistant "super gonohorrea" that will be incurable and essentially untreatable?

    So new public policy is no oral sex (gonohorrea) and condom usage?

    Speculate please.
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    Feb 19, 2015 7:10 PM GMT
    Svnw688 saidSo, not to chicken little, but what's the upshot of this?

    IF this "gets out" to the larger global community, we'll see dying in the streets like we did in the 80s because meds, effectively, won't work and it'll be like the days BEFORE we had these life-extending drugs?

    And this was caused because a poor country, produced ghetto and bootleg drugs?

    And this in conjunction with the impending drug resistant "super gonohorrea" that will be incurable and essentially untreatable?

    So new public policy is no oral sex (gonohorrea) and condom usage?

    Speculate please.


    That's very Chicken Little of you LOL

    "UPI notes however, 
”while the aggressive form of HIV responds to most antiretroviral drugs, people may not realize they have AIDS until it’s too late for treatment to do any good.”

    It's the speed of the strain that kills. They don't find out until it's too late. That can happen with the more familiar strains too. It happens here still where there is a reluctance to be tested.

    It sounds like PrEP would be especially useful in this scenario, to stay negative.

    The key word is "impending" gonorrhea resistance.
    The current failures are with mono-treatment (1 drug). As ART therapy has shown a multi-pronged drug approach prevents resistance. (Which may be Cuba's problem too, if they are having resistance problems with their HIV drugs).

    "The outlined treatment failures in Sweden were to stand-alone, monotherapy treatment of gonorrhea with ceftriaxone or cefotaxime. This treatment differs from the Centers for Disease Control’s recommended first-line treatment of gonorrhea which is: dual therapy of injectable ceftriaxone, in combination with one of two other oral antibiotics, either azithromycin or doxycycline."

    http://www.ncsddc.org/who-we-are/press-releases/gonorrhea-treatment-failures-sweden-highlighted
  • Giewald

    Posts: 1

    Feb 19, 2015 7:21 PM GMT
    It's a well known fact some gay men a selfish and have no morals concerning bareback sex and HIV no wonder it's spreading
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    Feb 19, 2015 7:43 PM GMT
    Giewald saidIt's a well known fact some gay men a selfish and have no morals concerning bareback sex and HIV no wonder it's spreading


    1st post eh?

    So it's a "fact"? Selfishness and morality are not factual. Your opinion is nothing more than that, an opinion....and a stigmatizing, blaming, lying one at that.

    Most cases of new HIV infections are from people who don't know and don't get tested.
  • Svnw688

    Posts: 3350

    Feb 19, 2015 10:42 PM GMT
    Seriously question, so this new "strain" that leads to AIDS sooner, and therefore leaves less room for drug intervention and control, is it going to leave Cuba? Has it already left Cuba? Could this become the dominant strain worldwide?

    I'm not trolling, I'm curious, and I can't find any information on this. I read the original article. Okay, so now what, where is this story going? What's the upshot?
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    Feb 19, 2015 10:57 PM GMT
    Svnw688 saidSeriously question, so this new "strain" that leads to AIDS sooner, and therefore leaves less room for drug intervention and control, is it going to leave Cuba? Has it already left Cuba? Could this become the dominant strain worldwide?

    I'm not trolling, I'm curious, and I can't find any information on this. I read the original article. Okay, so now what, where is this story going? What's the upshot?


    Well it came to Cuba from somewhere. Unless their crappy home made, half-assed meds caused the resistance/mutation. Still, ART still works. PrEP still works.

    If I were negative I'd even more inclined to use PrEP. I'm Poz/undetectable, on ART therapy. I doubt even a new strain will have an affect.

    I doubt it will become the main strain. If it did come from somewhere else, it's not widespread. If it was 'invented' in Cuba it's a closed environment, not likely to spread. By it's very nature it will die out quickly, along with the host.
  • Svnw688

    Posts: 3350

    Feb 19, 2015 11:14 PM GMT
    @Timm55, thanks.

    Well, I feel horrible for the people who caught this particular strain. HIV, in all its forms, is lame. But it's usually manageable. This strain, it seems, is not manageable unless you're getting regularly tested. I'm assuming most people, Cuba included, are not.

    This is all the more reason to get tested at least twice a year, wear condoms consistently, and consider PrEP.

    Be safe guys!