For a number of years my regular gay club in an upper-midwest US city was the only one within 200 miles. Literally. So it was one-size-fits-all.
We had gays, lesbians, trannies, bears, leather guys, twinks, drag queens, etc, the whole LGBT spectrum. But also a good number of straight college students from the 3 nearby universities.
For some of them it was a wicked pleasure, featuring the best DJ and techno dance floor in the entire region, a strong draw for the college crowd. When most of the other area bars and clubs offered CW boredom.
The girls would arrive in packs, I presume for mutual support. Sometimes they'd drag along their obviously uncomfortable boyfriends, who were grimly determined to defend their masculine reputations, scowling at the gay patrons the whole time.
And these girls would be loudly screaming & squealing constantly, I have no idea why. Excitement? I can't guess. And our bar room, separate from the dance room, was normally rather quiet. Men normally don't squeal like that, certainly not in that octave, and disrupt the peace of others.
Their sullen BFs, on the other hand, would skulk at the bar. If you went for a drink next to one of them you might be peremptorily informed: "I'm not gay! I'm with HER!" "Fine, I'm not interested in you OR her. My boyfriend's over there."
So the mix was kinda awkward. And really disruptive at times.
Here in Wilton Manors we routinely bring our straight women friends to our restaurants & clubs. In fact, we're scheduled to take my husband's (SB Alert) straight sister to one this Thursday. I love hosting straight women at our frequent haunts, I consider it good gay PR. But then in our age demographic, I doubt any of them will break into screams & shrieks.