Stem Cell cure for HIV?

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    Feb 12, 2009 9:08 PM GMT
    You can read the article below. Seems Stem cells transplants may cure HIV.

    If this is true could it be why the leadersof the republicans (Pres. Bush) and the christian rights wing (Pope) were against it all this time? I know conspiracy thoughts but think about it.

    If they knew say even for the past few years that studies showed it could cure HIV it might also give thought to why the religious right and President Bush were so against it. For if it could cure HIV then what fear could they instill into the general public about HIV. It would give them one less BIG arguement against gay rights.

    Thoughts?




    Stem-Cell Transplant Seemingly Eradicates Patient’s HIV
    by Kilian Melloy
    EDGE Contributor
    Thursday Feb 12, 2009



    Dr. Gero Hutter

    A man who received a bone marrow transplant from a donor carrying an unusual genetic mutation may have garnered an extra benefit: he was HIV positive before the procedure, but now there seems to be no trace of the virus in his system.

    The news broke late last year, but even then doctors were only cautiously optimistic, pointing out that the virus has a way of going into hiding in the body’s tissues, only to re-emerge later on.

    But the unidentified patient, who received the transplant as part of a treatment for leukemia, continues to test negative for HIV two years after the procedure, and his case has just been published in the prestigious New England Journal of Medicine, conferring upon the seeming miracle of science an imprimatur of serious medical interest in what the result might mean for future treatment options.

    However, the exact confluence of factors that worked in favor of the seemingly HIV-free patient would be next to impossible to arrange for most people--and not at all possible, at this point, for non-Caucasians.

    The mutation carried by the donor is present only in a tiny minority of Causcasians of European descent. The donor, who was a tissue match for the recipient, would not have been able to supply his marrow to most of the Caucasian population at large; and even with a good tissue match, the cure carries some of the same risks as the disease, because it is often necessary for transplant recipients of all sorts to undergo a life-long regimen of anti-rejection drugs, which act by suppressing the body’s immune system.

    And that’s assuming a happy outcome for the transplant procedure. As a Feb. 11 article at CNN.com reported, such transplants require that the patient’s own immune system be all but destroyed at the outset. University of California San Franciso professor Dr. Jay Levy was quoted in the article as noting that, "About a third of the people die, so it’s just too much of a risk."

    Then there are the enormous costs to consider: such treatments are resource intensive and expensive, far too much so to make such procedures commonplace for HIV/AIDS treatments.

    However, the choice of donor was not an accident, but rather a fortuitous case of several factors working out in a way that allowed doctors treating the patient for leukemia to make use of a compatible donor’s stem cells, with the added bonus that the donor had inherited the mutation from both parents, making him ideal for the secondary goal of seeing whether his stem cells could suppress HIV in the recipient.

    The mutation affects one of the co-receptor sites used by HIV to hijack the body’s T-cells.

    But people blessed with the mutation are not entirely invulnerable: CD-4 receptors are still present on their T-cells, and there are strains of HIV (which is a quickly-adapting virus) that can use other co-receptors.

    The American received treatment from a team of doctors in Berlin. The CNN article cited Charite Univbersitatsmedizin Berliln’s Dr. Gero Hutter, who said, "Today, two years after his transplantation, he is still without any signs of HIV disease and without antiretroviral medication."

    Added Dr. Hutter, "There is no really conclusive explanation why we didn’t observe any rebound of HIV," despite the patient’s not having returned to antiretrovirals after his treatment for leukemia.

    Added Hutter, "This finding is very surprising."

    But perhaps not a true cure, cautioned Dr. Levy, who was quoted as saying, "This type of virus can infect [other sorts of immune cells] and other cells, like the brain cells, and it could live a lifetime.

    "But if it can’t spread, you never see it," Levy added, going on to note, "but it’s there and it could do some damage."

    Said Levy, "It’s not the kind of approach that you could say, ’I’ve cured you.’ I’ve eliminated the virus from your body."

    Even so, the result is impressive enough to start researchers thinking about gene therapies to target T-cell receptor sites in the hopes of eventually making them unusable by the virus.

    Said Levy, "It’s definitely the wave of the future.

    "As we continue to follow this one patient, we will learn a lot."

    Noted Hutter, "For HIV patients, this report i
  • MikePhilPerez

    Posts: 4357

    Feb 12, 2009 9:15 PM GMT
    Cowboiway saidYou can read the article below. Seems Stem cells transplants may cure HIV.

    If this is true could it be why the leadersof the republicans (Pres. Bush) and the christian rights wing (Pope) were against it all this time? I know conspiracy thoughts but think about it.

    If they knew say even for the past few years that studies showed it could cure HIV it might also give thought to why the religious right and President Bush were so against it. For if it could cure HIV then what fear could they instill into the general public about HIV. It would give them one less BIG arguement against gay rights.

    Thoughts?


    I think you think too much. That is just nonsense. I understand the argument against stem cell research and it has nothing to do with the gay issue.
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    Feb 12, 2009 9:26 PM GMT
    I dunno. We all know that US Republicans want gays dead. I realize a few die-hard, brain-dead Republican advocates in RJ will dispute this, but the facts are clear. The Republican Party opposes gays at every point, and that's indisputable, based on the record.

    Now whether such a stem cell approach will defeat HIV isn't clear. And I can't determine whether Republicans have been aware of this possibility, and so therefore have been opposed to it on that hateful basis, or whether Republicans opposed stem cell research on purely Christian fundamentalist theology, which they are bound to do.

    But in any case Republicans no longer represent the interests of all the voters, but of Bible-thumping fundamentalists, who make up their electoral base. Stem cell research, though it may save countless lives, isn't compatible with those religious beliefs. Therefore it is opposed by Republicans, regardless of how many will die, in order to pander to their fundamentalist base, and get themselves reelected.

    The Republican Party is the greatest evil since Hitler and Stalin. Its destruction should be the goal of every patriot American, gay or straight.
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    Feb 12, 2009 9:57 PM GMT
    This doesn't make much sense. The article was published today and had been floating around for around a year, according to to the article.

    GOP opposition to stem cell research is way older than that and did not stem from a desire for queer genocide, but that other political cash cow: abortion. Now, some RJ members don't want to hear this because they are brain-dead.
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    Feb 12, 2009 10:22 PM GMT
    Republican conspiracy is one of the most absurd things I have ever heard, from both a political and scientific point of view. Social conservatives have a modestly legit reason to not like EMBRYOLOGICAL stem cell research: a fear that embyros will be created only to be killed. This would be akin to abortion.

    The stem cell treatments described in this study are completely different because the cells are not of embyro origin and in fact research of this nature was triumphed by Republicans as a sufficient alternative to the former.

    A stem cell is merely a cell that can do one of two things a) divide into more stem cells or b) specialize into more specific cells (lung, kidney, muscle or even immune cells like in this case). When you're conceived, you're basically only stem cells, but as you age you really don't have too many (if any) complete stem cells left. Instead you have "immune stem cells" or "liver stem cells." These can divide into a specific type of cell but not ANY type of cell.

    The bone marrow is basically a reservoir for blood stem cells. These are the cells that become red blood cells for carrying oxygen and white blood cells (or immune cells, the type HIV patients get infected by). Bone marrow or "immune stem cell" transplants have been going on for years to treat cancers of the immune system.

    This research suggests if you transplant the bone marrow (or again "immune stem cells) of a person who has a genetic immunity to HIV (~1% of the white population), then the person receiving the transplant will also have immunity to HIV
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    Feb 12, 2009 10:25 PM GMT
    Been hearing about this for a while now.

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    Feb 12, 2009 10:28 PM GMT
    As far as conspiracies go... let's just say I know a lot that may or may not be false though I don't know what is true and what is not.
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    Feb 12, 2009 10:39 PM GMT
    They say it could also cure Huntington's as well.

    If you have nursed a person dieing of this. You would know how cruel it really is.
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    Feb 12, 2009 10:41 PM GMT
    Most of the time conspiracies are just made up by people with too much time who think they understand the whole picture.

    Hey, did you know the Secret Service shot JFK so the brass-head generals could drag up into Veitnam?

    And Elvis is my next-door neighbor... shhh he dresses in drag now.

    Despite my distatse for some republicans and the fact that i disagree with mostly every issue a social consverative brings up... I do not think they would want to destroy the queers.

    These people are actually quite smart and organized--though I believe they are misgurided, not hateful--they must know HIV will never kill off gay people completely.

    OH I almost forgot, Bush also planned out 9/11! Hmm , it makes perfect sense. He allowed 3,000 Americans to die so he could have a reason to invade Iraq, de-throne Hussein, and redeem his daddy's imagine.
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    Feb 12, 2009 10:50 PM GMT
    cjcscuba1984 saidMost of the time conspiracies are just made up by people with too much time who think they understand the whole picture.

    Hey, did you know the Secret Service shot JFK so the brass-head generals could drag up into Veitnam?

    And Elvis is my next-door neighbor... shhh he dresses in drag now.

    Despite my distatse for some republicans and the fact that i disagree with mostly every issue a social consverative brings up... I do not think they would want to destroy the queers.

    These people are actually quite smart and organized--though I believe they are misgurided, not hateful--they must know HIV will never kill off gay people completely.

    OH I almost forgot, Bush also planned out 9/11! Hmm , it makes perfect sense. He allowed 3,000 Americans to die so he could have a reason to invade Iraq, de-throne Hussein, and redeem his daddy's imagine.


    You innocence and naivety shows in your youth. If you think that people like President Bush and other high ranking officals can not control research results. Hide documents and twist the truth to thier advantage. Conspiracies are not always made up. There are many with documented proof to many therories.

    You should wake up and learn some thing scuba..being 20yo and in college you still have a lot to learn.

    There have been many things kept from the public until someone leaked a secret.

    Is it so far fetched to think that some high ranking offical Like the Vatican or Whitehouse could keep such results secret?
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    Feb 12, 2009 10:54 PM GMT
    cjcscuba1984 saidMost of the time conspiracies are just made up by people with too much time who think they understand the whole picture.

    Hey, did you know the Secret Service shot JFK so the brass-head generals could drag up into Veitnam?

    And Elvis is my next-door neighbor... shhh he dresses in drag now.

    Despite my distatse for some republicans and the fact that i disagree with mostly every issue a social consverative brings up... I do not think they would want to destroy the queers.

    These people are actually quite smart and organized--though I believe they are misgurided, not hateful--they must know HIV will never kill off gay people completely.

    OH I almost forgot, Bush also planned out 9/11! Hmm , it makes perfect sense. He allowed 3,000 Americans to die so he could have a reason to invade Iraq, de-throne Hussein, and redeem his daddy's imagine.


    But..... It was the American Government who released the Virus, to get rid of the homosexual community in the USA. Jimmy Carter did it.

    Oh and Process Dianna works in a brothel in Sydney too.
  • DuggerPDX

    Posts: 386

    Feb 12, 2009 10:57 PM GMT
    My partner is a physician (pathologist) and my brother has MS, my partner just sent me this link to a study on stem cell therapy possibly working on MS.

    http://links.mkt292.com/servlet/MailView?ms=Mzg4MjMxNQS2&r=MTE0MzEwNDgyOAS2&j=MTA4OTA2MzgyS0&mt=1&rt=0

  • jlly_rnchr

    Posts: 1759

    Feb 12, 2009 11:06 PM GMT
    I didn't read everyone's response, so I'm sure this was already pointed out, but the stem cells used in this procedure are not the stem cells that the GOP/Bush have been up in arms about.

    Bush is anti embryonic stem cells. The ones extracted from a very early stage of an embryo.

    Stem cells in bone marrow are adult stem cells, which really just make blood cells. The embryonic stem cells could potentially make any cell type you tell them.

    Plus, Bush is illiterate and doesn't understand science, which kind of nullifies his ability to develop such an elaborate conspiracy.
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    Feb 12, 2009 11:12 PM GMT
    Cowboiway said
    cjcscuba1984 saidMost of the time conspiracies are just made up by people with too much time who think they understand the whole picture.

    Hey, did you know the Secret Service shot JFK so the brass-head generals could drag up into Veitnam?

    And Elvis is my next-door neighbor... shhh he dresses in drag now.

    Despite my distatse for some republicans and the fact that i disagree with mostly every issue a social consverative brings up... I do not think they would want to destroy the queers.

    These people are actually quite smart and organized--though I believe they are misgurided, not hateful--they must know HIV will never kill off gay people completely.

    OH I almost forgot, Bush also planned out 9/11! Hmm , it makes perfect sense. He allowed 3,000 Americans to die so he could have a reason to invade Iraq, de-throne Hussein, and redeem his daddy's imagine.


    You innocence and naivety shows in your youth. If you think that people like President Bush and other high ranking officals can not control research results. Hide documents and twist the truth to thier advantage. Conspiracies are not always made up. There are many with documented proof to many therories.

    You should wake up and learn some thing scuba..being 20yo and in college you still have a lot to learn.

    There have been many things kept from the public until someone leaked a secret.

    Is it so far fetched to think that some high ranking offical Like the Vatican or Whitehouse could keep such results secret?


    HAHA... another chance to look down apon me eh, Cowboi? I'm over that last debate. it seems appaernat you have something with younger guys and guys in college. And I am 24 yrs old my friend... which is actually a big differecne in the developement of young adults. But this line is classic: "...being 20yo and in college you still have a lot to learn."icon_rolleyes.gif


    Another thing, I did a 20 page paper concerning how the Bush Administration has hidden documents, skewed data, and prevented the professional expression of ideas of some scientists; all this hidden data concerned the reality and scientific evidence of anthropogenic climate change. I read a 40 page bipartisan document from the US House based on this cover-up.

    But where is your proof? Proof that Bush and the pope were hidding this data? Show me proof or enough proof to actually respect this conspiracy theory. If you can't... it has no credibility in my eyes. Now that is not to say that you are wrong... I just need proof before I go and blame certain people for moral corruption on a scale analogous to Adolf Hitler.
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    Feb 12, 2009 11:14 PM GMT
    Stem cells seem to hold the smallest, most concentrated form of life and healing we'll ever know. I am far from a scientist and understand very little, except that I have great hope that those who are smart enough will use this gift responsibly, cure the sick, heal the wounded and do so with as little loss of life as possible -- even life so small we cannot see.
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    Feb 12, 2009 11:18 PM GMT
    jlly_rnchr said
    Plus, Bush is illiterate and doesn't understand science, which kind of nullifies his ability to develop such an elaborate conspiracy.


    Oh How trueicon_biggrin.gif But at least doesn't have "Nu-cue-lar" weapon launching capabilities anymore.icon_razz.gif