Methicillin resistant Staph aureus (MRSA) is a problem, but part of that depends on where it was acquired and the actual resistance pattern. It used to be seen almost exclusively in chronically ill people, or those who had been hospitalized (and in health-care workers). However, in the past couple years MRSA has become fairly common in the general population as well. The community-acquired MRSA still tends to be sensitive to several common antibiotics that can be taken by mouth. There is some disagreement in the infectious disease (ID) field about treating contacts with nasal antibiotic ointment (like Bactroban). Again, when MRSA was less common, it was aggressively promoted as a way of preventing spread. However, now that it is so common, some ID specialists are saying the antibiotic ointment doesn't make any difference. It is easy, cheap, and can't hurt, though.