I'm not into going to loud bars and screaming to have a conversation over the relentless music. I come from a poor, Southern, and very large extended family where the traditional entertainment is sitting around the table talking and playing games until the wee hours of the night.
I have a group of friends I met in college who feel the same way, and we've been having regular game nights (4-5 times a month) for about seven years. I find that there's some psychological component that goes along with this tendency -- it consistently seems that people who don't like to sit and play table games end up being the kind of people I don't have enough in common with to become good friends. I think a lot of it has to do with the simplicity of stimulation. I see a lot of people who constantly need some flashbang external source of entertainment -- watching TV, going to a movie, going to a dance club. I think sitting around a table for 3-8 hours playing games and talking takes a good bit of empathy, intellect, focus, conversational skills, humility, and a sense of humor. You can quickly learn a lot about who someone really is on the inside by observing how they interact in a game situation.
Our favorite card game, by far, is Hand and Foot. It's one of those games with rules that seem arbitrary when you first learn them, but after a few times there's something undeniably addictive about it. It helps that it can easily be adapted for individual play or team play since we sometimes have 3 people and sometimes as many as 9 playing at once. It's also the kind of game that doesn't require you to remember a lot of detail about who played what and when, so the group can really focus and finish in as little as an hour and a half OR take a conversational detour every so often and easily pick up the game where we left off.
We also play a lot of Phase 10, Rage, and Mao.
Whenever we want a break from card games, we'll go for the classic southern domino games like Chicken Foot, 42, and Mexican Train.