Can't digest or metabolize certain alcohols

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    Oct 04, 2009 5:57 AM GMT
    So wierdest thing happens to me when i try to drink tequila straight or anything with tequila in it... it sits in my stomach for a couple hours, i dont get drunk, then I puke...

    anyone else have this problem with any kind of alcohol? its just tequila... i dont do shots often because of my size, but tequila does it every time... or is this some kind of medical thing?
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    Oct 04, 2009 6:15 AM GMT
    You're not alone, that's for sure.




    goggle this

    allergies to tequila?


    Seems it's not all that uncommon! Someone even wrote a site for a tequila-less margarita recipe as her friend loves wine etc but has a reaction to tequila. One site talked about something called blue agave being a problem.
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    Oct 04, 2009 7:59 AM GMT
    This happens only with tequila? Or all alcohol?
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    Oct 04, 2009 1:41 PM GMT
    Back in my drinking days, tequila always made me violently ill.
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    Oct 04, 2009 1:51 PM GMT
    tequila does this to me as well. it also feels like it strips the lining in my mouth and throat.
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    Oct 04, 2009 3:01 PM GMT
    I have the same problem. That's way I don't drink aymore.
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    Oct 04, 2009 3:10 PM GMT
    I drink extremely little these days - and really never did drink all that much. Once a few of my friends and I got pretty sick the following day after a party where the bartender ran out of vodka and switched some of us to gin - - - without asking us. Other than that - - no problems I can think of.
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    Oct 04, 2009 4:24 PM GMT
    There's only one kind of alcohol that you drink and that is ethanol. Whether its tequila, vodka, gin, whiskey, beer, or wine. The alcohol is the same.

    It is the flavorings/additives/distillates/sweeteners etc. and water that vary from one kind of drink to another.

    Different people can have reactions to certain additives over another. Everyone takes in alcohol the same which is why alcohol blood tests are fairly consistent. If you have trouble metabolizing alcohol, then it won't vary with the source of the alcohol. Certain medications can affect your metabolizing alcohol which can lead to the 'antabuse' effect, which if not addressed can kill.

    Antabuse was a drug meant to be used by alcoholics to make them violently ill if they drank even a small amount of alcohol. It worked by preventing your system from fully metabolizing alcohol. I believe that it is no longer in use because of the fact that someone on it, if they drank too much before the alcohol began to metabolize in their system, the effect could cause fatal heart attacks or seizures. Certain drugs for other conditions also have an atabuse effect but patients that are given these drugs are warned specifically and strongly about it.
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    Oct 04, 2009 4:25 PM GMT
    Tequila, Vodka and Budweiser ( singly, not mixed together) always gave me headaches. Since I no longer drink, problem solved.icon_wink.gif
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    Oct 04, 2009 5:13 PM GMT
    The only thing I drink is guiness. I could have 1 light american beer and still feel bad the next day. A rum and coke hurts my stomach. wine can't get past my lips. I thought I would not drink any alcohol until I tried guiness. Must be the barley and hops, but I feel good the next day, even if I have 1 or 8 of them.

    The human body...interesting machine. The funny thing is alcohol is one of a few substance that is not digested by the stomach. Everything else is.
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    Oct 04, 2009 5:14 PM GMT
    I am one of those "light weights" that suffers genetically from "ALCOHOL FLUSH" http://en.wikipedia.org/wiki/Alcohol_flush_reaction....I lack the physical capacity to metabolize alcohol in a more "normal" or "average" quantity. Plus, when I had Weight Loss Surgery, my digestive track was forever altered and I have a very difficult time handling sugars (alcohol).
    The normal man can process 1 oz of alcohol per hour, it takes me 4 hours to process that same ounce of alcohol....so I get drunk faster on less alcohol and I stay drunk longer and it actually registers a BAC different from the little chart that is used by the police to calculate the number of drinks you had vs your weight and the BAC reading.......the only alcohol found in consumed drinks is supposed to be ethanol...if there is a different alcohol, someone is trying to poison you. Even in TEQUILA, the alcohol is ethanol.....plus the flavors and the colors and the traces of other chemicals, and whatever else is added...ice, salt, lemon/limes, mixers, etc... your story of "sensitivity" to alcohol is not that unusual.... if TEQUILA is making you puke and not getting you the buzz you want...DON'T drink it! Maybe you are allergic to "AGAVE" that the Tequila comes from...drink something else.icon_cool.gif
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    Oct 04, 2009 6:02 PM GMT
    Sporty_g saidI am one of those "light weights" that suffers genetically from "ALCOHOL FLUSH" http://en.wikipedia.org/wiki/Alcohol_flush_reaction....I lack the physical capacity to metabolize alcohol in a more "normal" or "average" quantity. Plus, when I had Weight Loss Surgery, my digestive track was forever altered and I have a very difficult time handling sugars (alcohol).
    The normal man can process 1 oz of alcohol per hour, it takes me 4 hours to process that same ounce of alcohol....so I get drunk faster on less alcohol and I stay drunk longer and it actually registers a BAC different from the little chart that is used by the police to calculate the number of drinks you had vs your weight and the BAC reading.......the only alcohol found in consumed drinks is supposed to be ethanol...icon_cool.gif


    Those are two separate things you're talking about. "Alcohol flush" which you mention at the beginning, is a genetic thing which is a problem with the acetyldehyde dehydrogenase cycle, not the alcohol dehydrogenase cycle. When you later talk about not being able to metabolise alcohol(ethanol) and getting drunk faster, it has nothing to do with the genetic 'alcohol flush' aspect since acetyldehyde doesn't make you drunk, only ethanol does. So if you now find yourself getting more drunk faster, it must be entirely due to the surgery, not the genetic condition.

    What's more, as a matter of statistics, the main populations which are studied with regards to the miscoded ALDH2 condition are of oriental decent where 50% actually have a ADH cycle which is MORE efficient; meaning they convert ethanol to acetaldehyde more quickly, losing the 'drunk' feeling faster. Unfortunately oriental groups suffer about 85-90% ALDH2 miscoding which results in a cycle which is only 25% as efficient as normal, so not only does the drunk feeling go faster, acetaldehyde is being produced much faster along with a greatly reduced ability to convert it further to carbon dioxide and water, increasing the symptoms we normally associate with a hangover. So in most documented population studies and statistics, the people suffering from 'alcohol flush' in fact don't get more drunk, but less drunk on the same amount of alcohol, because these populations which are studied are of oriental descent.

    We covered this topic in detail at a Master of Wine seminar a couple of years ago and it busted the myth for a lot of attendees who were experts in their own right.
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    Oct 04, 2009 6:03 PM GMT
    And a big sorry face icon_redface.gif for the (very cute) original poster, for going off topic....


    SNIP
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    Oct 04, 2009 6:19 PM GMT
    KyleAD saidSo wierdest thing happens to me when i try to drink tequila straight or anything with tequila in it... it sits in my stomach for a couple hours, i dont get drunk, then I puke...

    anyone else have this problem with any kind of alcohol? its just tequila... i dont do shots often because of my size, but tequila does it every time... or is this some kind of medical thing?


    Males of some races, and almost all women of all races, metabolism alcohol differently.

    Being so under-weight also almost certainly plays a factor.

    There may be drugs, or other factors that contribute to how you metabolize carbohydrates, and alcohol. If you aren't eating much, which it does appear that you are, sugars can have a dramatic effect when you ingest them.

    You'll probably want to eat.

    You may wish to google up on this for more details.
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    Oct 04, 2009 7:04 PM GMT
    If you must ingest cacti eat peyote instead,you will definately throw up but you wont get cheated of the buzz. It's fat free too.
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    Oct 04, 2009 11:50 PM GMT
    That's the thing... its ONLY tequila... any brand, any drink... the alcohol isnt absorbed... at all... I can drink vodka and sake, i can drink beer, i can drink high content wines... i'm not on any meds, don't have any known stomach issues.

    And I NEVER drink if i'm not eating... In fact, the only thing I'll drink without food is beer.
  • Anto

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    Oct 05, 2009 12:15 AM GMT
    Maybe you are allergic to the plant that tequila is made from?
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    Oct 05, 2009 12:23 AM GMT
    Vodka and I just dont mix... I can drink Tequilla like if it were water but Vodka... FORGET IT! Its almost as bad as me and beer.icon_eek.gif
  • EricLA

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    Oct 05, 2009 12:47 AM GMT
    I assume you're not mixing tequila with any other drinks, right? After a couple of beers or a glass of wine? That can end up with the results you're experiencing. But, in general I seem to know a few people who don't get along with tequila. I usually prefer it, because I tend not to get a hangover from the good stuff the way I would other alcohol. Must be the agave.
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    Oct 05, 2009 4:03 AM GMT
    haha yes definatly cant touch tequilla
    gives me a good buzz and then BAM i am coma
    kinda dangerous actually lucky i have good friends that helped me out in times like that.
    i have to drink and mix alot of alcohol to have the same effect as just a couple of shots, or a sunrise


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    Oct 05, 2009 4:09 AM GMT
    yeah tequila sits in my stomach for hours also,but I was too drunk to get up and make myself throw up.icon_confused.gif
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    Oct 05, 2009 4:14 AM GMT
    sooo true! for its Puerto Rican Rum....ugh I'm getting nauseous thinking about it....

    Mr. Walker also has a very strange affect on me....after a shot or 2 I start do things I will never remember and regret in the morning once the text messages start coming in!