My sister's in an abusive relationship, which is terrible. She takes it out on her son, which is worse. I can't deal with her issues of denial. I haven't seen her son in close to 10 years, partly b/c she doesn't want her son to be around a "fag," which is funny considering she's a dyke and her abusive partner is another woman.
My brother's a drug addict who lost everything, including his three boys and wife, a high six-figure salary, a beautiful home ... his entire life has been destroyed thanks to opiates. His life makes the television show, Intervention, look like Sesame Street.
To answer your question, no. I don't speak with my siblings at all. I certainly wouldn't choose to have them as friends. I moved to NYC to get away from people like that.