I had some ankle problems last year when I ramped up my marathon training. I never had problems before with the tennis shoes I wore at the time, but they were 3 year old shoes and had gotten old and worn out. One day after a long run my ankles hurt so bad. I waited a few days for the pain to go away, then I ran again in those shoes...and the problem came back. So I concluded that maybe they were the problem. A friend of mine suggested I go to one of the running specialty stores here in houston and have them help me get some new shoes. this place had me try on different shoes and they watched me run (I felt kinda silly running up and down store----but whatever helps). Apparently I am overly pronated, so they found me the right pair of shoes for it. I tried them out the next day and ran 6 miles and no more ankle problems! If you haven't tried it out already, I would recommend finding one of those stores around where you are that specializes in running and see if they can help you find a good pair of shoes. Granted---shoes aren't always the problem, but that's what helped me.