From the article in the first link in the first post:
Six products were studied. Five (Astroglide, Elbow Grease, ID Glide, KY Jelly and Wet Platinum) were selected because they had been identified as those most commonly used by the more than 6,300 respondents to an IRMA survey. The sixth product (PRÉ) was selected to serve as a control because it is isomolar. Osmolarity refers to the concentration of dissolved particles (salts and sugars) found inside a cell relative to the outside. A product that is isomolar has the same concentration of particles as inside the cell, whereas a product that is hyperosmolar has a higher concentration of salts and sugars relative to the cell. To correct this imbalance, a cell forces water out but then it becomes withered and dies.
Most of the lubricants studied were water-based, except for Wet Platinum, which is a condom-compatible silicone-based product. The researchers characterized each product according to its osmolarity, pH and viscosity -- or slipperiness. Studies then were conducted to determine the effect of each lubricant on different cell types, rectal and cervical tissue and on bacteria (microorganisms that are important to the health of the rectum). Based on the tests performed, PRÉ and Wet Platinum were shown to be safest, while Astroglide was the most toxic to cells and tissues, and KY Jelly had the worst effect on the good bacteria, essentially wiping out an entire colony. PRÉ was the only water-based lubricant that was not hyperosmolar and did not disrupt the epithelium.
None of the lubricants had measurable anti-HIV activity. In future studies, the researchers hope to determine the effect that different lubricants have on susceptibility to HIV infection in tissues.
Has anyone here tried PRÉ? I'm wondering how well it works for a lube.