I'd love to bike to work. At the moment, however, my commute to work is from my bed to my desk. So, no need to bike. I do however walk to the gym, grocery, drug store, restaurants, bars, etc... Everything I need on a regular basis is no more than 5 blocks from my house.
When I lived in the Caribbean, I would have biked to work, but it was way too dangerous. I would normally work until it was dark, and I didn't feel safe driving through some part of the island, much less riding my bike with my laptop on my back.
At least here in Florida, I wouldn't be comfortable biking to work unless it was VERY close because I'd be nasty by the time I got to work. Since my work is mainly in an office behind a computer, I would be miserable all day in sweaty clothes. So, unless there was a locker room at work, I can't see it happening. The weather (and my type of work) just doesn't permit it.
I'm also very leery of riding my bike in major roads. One of my best friends from school was struck by a car in NYC while riding her bike somewhere she did every week for years. Now she's a quadriplegic. I love riding a bike for exercise, but I think I'd stick to a place with trails or paths just for bikes. Drivers don't seem to ever pay attention to bikers.