A Supercomputer Analyzed Covid-19 — and an Interesting New Theory Has Emerged

  • metta

    Posts: 54709

    Sep 02, 2020 5:41 PM GMT
    A Supercomputer Analyzed Covid-19 — and an Interesting New Theory Has Emerged

    "According to the team’s findings, a Covid-19 infection generally begins when the virus enters the body through ACE2 receptors in the nose, (The receptors, which the virus is known to target, are abundant there.) The virus then proceeds through the body, entering cells in other places where ACE2 is also present: the intestines, kidneys, and heart. This likely accounts for at least some of the disease’s cardiac and GI symptoms."

  • Element1313

    Posts: 411

    Sep 03, 2020 12:33 PM GMT
    Mouth breathers come out on top in this pandemic.
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    Sep 04, 2020 1:24 AM GMT
    If it weren’t so uncomfortable, to the point of being intolerable, I wonder if wearing a swimmer’s nose clip under your mask would give you superior Covid protection. You’d still wear a mask, because that protects others from your breath and coughs. Of course if you sneezed you might blow your eardrums out. icon_eek.gif
  • mwolverine

    Posts: 7522

    Sep 04, 2020 4:10 AM GMT
    Yes, for those who wear their mask under the nose....

  • mwolverine

    Posts: 7522

    Sep 04, 2020 4:12 AM GMT
    From the published study:

    A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm

    Here, we present a novel molecular mechanism for COVID-19 that provides therapeutic intervention points that can be addressed with existing FDA-approved pharmaceuticals. The entry point for the virus is ACE2, which is a component of the counteracting hypotensive axis of RAS. Bradykinin is a potent part of the vasopressor system that induces hypotension and vasodilation and is degraded by ACE and enhanced by the angiotensin1-9 produced by ACE2. Here, we perform a new analysis on gene expression data from cells in bronchoalveolar lavage fluid (BALF) from COVID-19 patients that were used to sequence the virus. Comparison with BALF from controls identifies a critical imbalance in RAS represented by decreased expression of ACE in combination with increases in ACE2, renin, angiotensin, key RAS receptors, kinogen and many kallikrein enzymes that activate it, and both bradykinin receptors. This very atypical pattern of the RAS is predicted to elevate bradykinin levels in multiple tissues and systems that will likely cause increases in vascular dilation, vascular permeability and hypotension. These bradykinin-driven outcomes explain many of the symptoms being observed in COVID-19.

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    Sep 04, 2020 9:21 PM GMT
    For more than 150 years Vitamin D was known to be effective against certain respiratory diseases including TB. Cod Liver Oil was the principal source of Vitamin D back in those days...and it still is.

    The UK Government published a document produced by The Scientific Advisory Committee on Nutrition (SACN) back in 2016 which covers all aspects of Vitamin D and the fact that all of us need to increase the level of intake ....the link to the document is -


    Read it...and get dosing on Vitamin D...NOW...400IU or 800IU is the daily dose that is best...